Ignite Creation Date:
2024-10-26 @ 3:36 PM
Last Modification Date:
2024-10-26 @ 3:36 PM
Study NCT ID:
NCT06525324
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-07-19
Brief Title:
Comparision of Clinical Efficacy of Immediate Implants With T-PRF and Bone-graft Versus PRF and Bone-graft
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Comparing The Effectiveness Of T-PRF And PRF With Bone-GraftDMBMTM Around Immediate Implants - A RANDOMISED CONTROL TRIAL
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The normal architecture of the alveolar process is altered by periodontitis which also causes the loss of alveolar bone surrounding the teeth Untreated periodontitis may cause teeth to become mobile and leads to loss of teeth
In such cases one of the treatment modalities is extraction of the tooth and placement of immediate implant which reduces the waiting period And due to the resorption of alveolar ridge the bone graft will be used along with T-PRF and PRF
So this study aims at the placement of immediate implants along with T-PRF with bone graft and PRF with bone graft
In such cases one of the treatment modalities is extraction of the tooth and placement of immediate implant which reduces the waiting period And due to the resorption of alveolar ridge the bone graft will be used along with T-PRF and PRF
So this study aims at the placement of immediate implants along with T-PRF with bone graft and PRF with bone graft
Detailed Description:
Dental implants have become more common treatment for replacing missing teeth and aim to improve chewing efficiency physical health and esthetic And their will be resorption of alveolar process due to periodontitis In such compromised cases to achieve bone augmentation around immediately placed implants a new modality of using platelet rich fibrin PRF along with graft material has gained considerable interest
Successful clinical results have been reported with L-PRF but some physicians worry about a possible health hazard with glass-evacuated blood collection tubes with silica activators OConnell described the unavoidable silica contact The silica particles in the tube although dense enough to sediment with the red blood cells are small enough for a fraction to remain colloidally suspended in the buffy coat fibrin and platelet-poor plasma layers therefore these particles might reach the patient when the product is used for treatment
Recently use of titanium tubes in the preparation of PRF showed more polymerized fibrin formation with longer resorption in tissues as titanium seems to be more effective in activating platelets than silica and also eliminates the possible silica contamination
The use of T-PRFTitanium PRF along with xenograft creates a block graft with high concentrated growth factors platelets and leucocytes which enhance development of bone and eliminates the possible silica contamination
Hence the aim of the study is to compare the effectiveness of T-PRF with xenograft DMBM and PRF with xenograft DMBM around immediate implants
Successful clinical results have been reported with L-PRF but some physicians worry about a possible health hazard with glass-evacuated blood collection tubes with silica activators OConnell described the unavoidable silica contact The silica particles in the tube although dense enough to sediment with the red blood cells are small enough for a fraction to remain colloidally suspended in the buffy coat fibrin and platelet-poor plasma layers therefore these particles might reach the patient when the product is used for treatment
Recently use of titanium tubes in the preparation of PRF showed more polymerized fibrin formation with longer resorption in tissues as titanium seems to be more effective in activating platelets than silica and also eliminates the possible silica contamination
The use of T-PRFTitanium PRF along with xenograft creates a block graft with high concentrated growth factors platelets and leucocytes which enhance development of bone and eliminates the possible silica contamination
Hence the aim of the study is to compare the effectiveness of T-PRF with xenograft DMBM and PRF with xenograft DMBM around immediate implants
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None