Ignite Creation Date:
2024-10-26 @ 3:36 PM
Last Modification Date:
2024-10-26 @ 3:36 PM
Study NCT ID:
NCT06537726
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-07-27
Brief Title:
Breath Analysis for the Detection of Invasive Fungal Infections
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Real-time Breath Analysis for the Detection of Invasive Fungal Infections in Neutropenic High-risk Patients
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
REDEFINE
Brief Summary:
Patients with leukemia and concomitant neutropenia are at high risk of developing invasive fungal infections IFI that are associated with high morbidity and mortality As these patients typically have severe thrombocytopenia direct diagnostic sampling with invasive procedures is often not possible due to the high peri-interventional risk Therefore the presumptive diagnosis of IFI is primarily based on compatible lung findings on computed tomography and serologic detection of fungal cell wall components which however have limited sensitivity and specificity
With the present study the investigators aim to determine a set of specific volatile biomarkers in leukemia patients with proven or probable IFI using secondary electrospray ionization high-resolution mass spectrometry SESI-HRMS
With the present study the investigators aim to determine a set of specific volatile biomarkers in leukemia patients with proven or probable IFI using secondary electrospray ionization high-resolution mass spectrometry SESI-HRMS
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None