Ignite Creation Date:
2024-10-26 @ 3:37 PM
Last Modification Date:
2024-10-26 @ 3:37 PM
Study NCT ID:
NCT06540534
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-08-02
Brief Title:
Evaluation of Adjuvant Use in Selective Trunk Block
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Comparison of Anesthetic and Analgesic Efficacy of Dexamethasone as an Adjuvant in Selective Trunk Block
Status:
COMPLETED
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Evaluation of the Anesthetic and Analgesic Efficacy of Dexamethasone in Selective Trunk Blocks
Detailed Description:
the investigators hypothesize that the perineural application of dexamethasone as an adjuvant in selective trunk block for upper extremity surgeries will accelerate the onset time of anesthesia and analgesia provide significant anesthetic and analgesic effects and prolong the duration of anesthesia and analgesia
In recent years the brachial plexus block performed with various approaches has been preferred over general anesthesia for upper extremity orthopedic surgeries due to its numerous advantages It maintains the patients consciousness and spontaneous respiration reduces airway interventions provides effective postoperative pain control minimizes opioid-related side effects limits surgery-related metabolic and endocrine changes enables early discharge and reduces treatment costs
Selective trunk block offers rapid block onset and high success rates The use of ultrasound in peripheral blocks has also reduced the risk of various complications eg vascular injury The selective trunk approach as described by Manoj Kumar Karmakar in 2020 involves blocking the upper middle and lower trunks at the C7 transverse process level resulting in sensorymotor block in all ipsilateral upper extremity dermatomes except T2 This study aims to compare the anesthetic and analgesic efficacy of dexamethasone as an adjuvant to bupivacaine in the selective trunk block approach
Dexamethasone is a widely used glucocorticoid with anti-inflammatory anti-toxic and other effects It has strong lipophilic properties is soluble in fat increases pH facilitates the penetration of local anesthetics into nerve sheaths and extends the duration of local anesthetic effects as supported by various studies Additionally dexamethasone is commonly used in pain management for its neuromodulatory effects
In recent years the brachial plexus block performed with various approaches has been preferred over general anesthesia for upper extremity orthopedic surgeries due to its numerous advantages It maintains the patients consciousness and spontaneous respiration reduces airway interventions provides effective postoperative pain control minimizes opioid-related side effects limits surgery-related metabolic and endocrine changes enables early discharge and reduces treatment costs
Selective trunk block offers rapid block onset and high success rates The use of ultrasound in peripheral blocks has also reduced the risk of various complications eg vascular injury The selective trunk approach as described by Manoj Kumar Karmakar in 2020 involves blocking the upper middle and lower trunks at the C7 transverse process level resulting in sensorymotor block in all ipsilateral upper extremity dermatomes except T2 This study aims to compare the anesthetic and analgesic efficacy of dexamethasone as an adjuvant to bupivacaine in the selective trunk block approach
Dexamethasone is a widely used glucocorticoid with anti-inflammatory anti-toxic and other effects It has strong lipophilic properties is soluble in fat increases pH facilitates the penetration of local anesthetics into nerve sheaths and extends the duration of local anesthetic effects as supported by various studies Additionally dexamethasone is commonly used in pain management for its neuromodulatory effects
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None