Ignite Creation Date:
2024-10-26 @ 3:37 PM
Last Modification Date:
2024-10-26 @ 3:37 PM
Study NCT ID:
NCT06541262
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-08-02
Brief Title:
Silmitasertib CX-4945 in Combination with Chemotherapy for Relapsed Refractory Solid Tumors
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Phase III Study of Silmitasertib CX-4945 in Combination with Chemotherapy in Children and Young Adults with Relapsed Refractory Solid Tumors
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to evaluate the investigational drug silmitasertib a pill taken by mouth in combination with FDA approved drugs for solid tumors An investigational drug is one that has not been approved by the US Food Drug Administration FDA or any other regulatory authorities around the world for use alone or in combination with any drug for the condition or illness it is being used to treat
The goals of this part of the study are
Establish a recommended dose of silmitasertib in combination with chemotherapy
Test the safety and tolerability of silmitasertib in combination with chemotherapy in subjects with cancer
To determine the activity of study treatments chosen based on
How each subject responds to the study treatment
How long a subject lives without their disease returningprogressing
The goals of this part of the study are
Establish a recommended dose of silmitasertib in combination with chemotherapy
Test the safety and tolerability of silmitasertib in combination with chemotherapy in subjects with cancer
To determine the activity of study treatments chosen based on
How each subject responds to the study treatment
How long a subject lives without their disease returningprogressing
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None