Ignite Creation Date:
2024-10-26 @ 3:37 PM
Last Modification Date:
2024-10-26 @ 3:37 PM
Study NCT ID:
NCT06542107
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-08-02
Brief Title:
Weaning From Mechanical Ventilation in Patients With Acute Brain Injury
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Prediction of Weaning for Patients With Acute Brain Injury Undergoing Mechanical Ventilation
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Acute brain injury ABI patients frequently necessate intubation and invasive mechanical ventilation IMV While some ABI patients are capable of breathing spontaneously which is one of the main criteria of extubation and weaning However the rate of extubation failure was significantly higher in ABI patients compared with non-neurological critical care patients In patients who have failed one or several trials of extubation tracheostomy is recommend according to the latest ESICM consensus Tracheostomy can enhance comfort improve pulmonary hygiene and decrease sedation requirement which could facilitate the liberation from ventilator
Numerous studies have explored the causes of weaning failure and provide various predictive models in guiding extubation and tracheostomy Yet due to limitations of such as small sample size or a lack of external validation there is paucity of practical weaning algorithm tailored for ABI patients The liberation from IMV in ABI patients still remains challenging with poor level of evidence in current guidelines or expert consensus
We aim to describe the weaning outcomes in ABI patients and further investigate the potential predictors of weaning success in ABI patients
Numerous studies have explored the causes of weaning failure and provide various predictive models in guiding extubation and tracheostomy Yet due to limitations of such as small sample size or a lack of external validation there is paucity of practical weaning algorithm tailored for ABI patients The liberation from IMV in ABI patients still remains challenging with poor level of evidence in current guidelines or expert consensus
We aim to describe the weaning outcomes in ABI patients and further investigate the potential predictors of weaning success in ABI patients
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None