Ignite Creation Date:
2024-10-26 @ 3:37 PM
Last Modification Date:
2024-10-26 @ 3:37 PM
Study NCT ID:
NCT06545981
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-06-12
Brief Title:
Ocular Perfusion in Patients With Idiopathic Intracranial Hypertension
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Ocular Perfusion in Patients With Idiopathic Intracranial Hypertension
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The proposed study aims to evaluate optic nerve head blood flow and microcirculation in patients with idiopathic intracranial hypertension For this purpose optic nerve head blood flow will be examined in patients with IIH before and after therapy and additionally compared with healthy age- and sex-matched control subjects In addition other parameters will be measured in particular retinal blood flow retinal oxygen saturation and retinal neurovascular coupling
Detailed Description:
Idiopathic intracranial hypertension IIH is a neuroophthalmological disease characterized by an increased intracranial pressure ICP without an identifiable causative factor If not properly treated and carefully monitored the disease can even lead to irreversible severe or complete loss of vision or severe irreversible visual field defects respectively Given this clinical urgency precise diagnostic tools become essential for timely decision making
Laser Speckle Flowgraphy LSFG is a non-invasive in-vivo imaging method which quantitatively estimates blood flow in the optic nerve head the choroid the retina and the iris LSFG has a low procedural complexity obtains precise and reproducible measurements and is therefore suitable to assess ocular perfusion
The proposed study aims to evaluate optic nerve head blood flow and microcirculation in patients with idiopathic intracranial hypertension For this purpose optic nerve head blood flow will be examined in patients with IIH before and after therapy and additionally compared with healthy age- and sex-matched control subjects In addition other parameters will be measured in particular retinal blood flow retinal oxygen saturation and retinal neurovascular coupling
Laser Speckle Flowgraphy LSFG is a non-invasive in-vivo imaging method which quantitatively estimates blood flow in the optic nerve head the choroid the retina and the iris LSFG has a low procedural complexity obtains precise and reproducible measurements and is therefore suitable to assess ocular perfusion
The proposed study aims to evaluate optic nerve head blood flow and microcirculation in patients with idiopathic intracranial hypertension For this purpose optic nerve head blood flow will be examined in patients with IIH before and after therapy and additionally compared with healthy age- and sex-matched control subjects In addition other parameters will be measured in particular retinal blood flow retinal oxygen saturation and retinal neurovascular coupling
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None