Ignite Creation Date:
2024-10-26 @ 3:37 PM
Last Modification Date:
2024-10-26 @ 3:37 PM
Study NCT ID:
NCT06547190
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-07-31
Brief Title:
Study on Treating by Eating Role of AGEs on Mucosal Barrier and Microbiome
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Study on Treating by Eating Role of AGEs on Mucosal Barrier and Microbiome
Status:
COMPLETED
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
STEAMM
Brief Summary:
This is an exploratory study aimed at healthy volunteers to investigate the impact of differential cooking methods on global and gut inflammation intestinal permeability and the gut microbiota The investigators hypothesize that a short dietary intervention of baking and grilling of food for 2 weeks as opposed to steaming and boiling of food for 2 weeks will result in measurable differences in blood stool and urine samples that guide towards gut and overall health and disease All food will be provided together with detailed cooking instructions Food logs including photographs will be used to check whether participants complied with the study
The investigators aim to better understand the role of cooking methods in human health so that this can be implemented in preventive strategies and dietary treatments for specific patient groups
The investigators aim to better understand the role of cooking methods in human health so that this can be implemented in preventive strategies and dietary treatments for specific patient groups
Detailed Description:
This is a pilot project aimed at healthy volunteers to investigate the impact of differential cooking methods on systemic and intestinal inflammation permeability and the gut microbiota using a randomised cross-over design The investigators hypothesize that a short dietary intervention of baking and grilling of food for 2 weeks high-Advanced Glycation End Products AGEs diet as opposed to steaming and boiling of food for 2 weeks low-AGEs diet will result in measurable differences in inflammatory cardiometabolic and microbial markers in blood and stool as well as changes in intestinal permeability through their effect on dietary AGEs All food will be provided together with detailed cooking instructions Food logs including photographs will be used to assess and check adherence to the intervention
The investigators aim to better understand the role of cooking methods and thermal treatments in human health so that this can be implemented in preventive strategies and dietary treatments for specific patient groups
The investigators aim to better understand the role of cooking methods and thermal treatments in human health so that this can be implemented in preventive strategies and dietary treatments for specific patient groups
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None