Viewing Study NCT06547372



Ignite Creation Date: 2024-10-26 @ 3:37 PM
Last Modification Date: 2024-10-26 @ 3:37 PM
Study NCT ID: NCT06547372
Status: RECRUITING
Last Update Posted: None
First Post: 2024-08-02

Brief Title: Dietary Intervention on Atopy
Sponsor: None
Organization: None

Study Overview

Official Title: Dietary Intervention on Atopy
Status: RECRUITING
Status Verified Date: 2024-08
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: No
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Dietary habits play an indispensable role in maintaining overall health and well-being In recent years emerging research has underscored the importance of dietary factors on a range of diseases which include allergic atopic diseases such as atopic dermatitis AD Conducting a dietary intervention study related to AD can provide valuable insights into the relationship between diet and the development or management of this particular allergic skin condition
Detailed Description: Atopic dermatitis AD is a chronic inflammatory skin disease highly associated with xerosis and pruritus affecting a substantial portion of individuals of all age groups The European Academy of Allergy and Clinical Immunology EAACI Task Force on Diet and Immunomodulation also emphasized the role of dietary patterns as an important indicator to study the risk of allergic diseases Furthermore emerging epidemiological findings and randomised controlled trials RCT in recent decades strongly suggest that diet may play a pivotal role in not only triggering and exacerbating AD but also in its effective management

Preliminary cross-sectional findings in a large independent allergic cohort of 13561 young Chinese Adults from Singapore and Malaysia highlighted that a frequent intake of high-fat foods such as margarine butter seafood and burgers and fast foods is strongly associated with a higher risk of AD A diet consisting mainly of high-fat foods or a high-fat diet as shown by a derived amount- and score-based dietary indices was strongly associated with a higher risk for severe AD even controlling for potential confounding factors like age sex body mass index BMI lifestyle habits and genetic predisposition On the other hand a frequent adherence to a plant-based food dietary pattern consisting of fruit vegetables and cereals was associated with a lowered risk of severe AD Overall these compelling findings aligned with evidence-based guidelines such as My Healthy Eating Plate Singapore a visual guide designed to promote a balanced and nutritious dietary pattern specific to the Singaporean context

In conclusion a whole diet dietary intervention on AD that adhere to established dietary recommendations such as My Healthy Eating Plate Singapore may offer a promising avenue for individuals seeking to i improve AD symptoms ii improve skin health and iii improve quality-of-life

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None