Ignite Creation Date:
2024-10-26 @ 3:37 PM
Last Modification Date:
2024-10-26 @ 3:37 PM
Study NCT ID:
NCT06551168
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-08-09
Brief Title:
Heat Acclimation in Females
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The Cardiovascular Hematological and Performance Response to Heat Acclimation in Healthy Trained Females
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Heat acclimation is when you repeatedly exposure yourself to heat so that your body adapts and better tolerates heat
This project will determine if completing a heat acclimation maintenance period after heat acclimation is more beneficial than heat acclimating alone for exercise performance in the heat To determine this participants will exercise in the heat before heat acclimation after heat acclimation and after heat acclimation maintenance Researchers will assess the hearts pumping capacity blood volume body temperature and exercise performance to determine which approach is more effective
This project will determine if completing a heat acclimation maintenance period after heat acclimation is more beneficial than heat acclimating alone for exercise performance in the heat To determine this participants will exercise in the heat before heat acclimation after heat acclimation and after heat acclimation maintenance Researchers will assess the hearts pumping capacity blood volume body temperature and exercise performance to determine which approach is more effective
Detailed Description:
Purpose and Hypothesis Global warming combined with increased frequency of heat waves exposes those who are working exercising or competing outdoors to considerable thermal strain Excessive heat stress decreases exercise performance and can lead to heat illnesses Deliberate serial exposure to natural acclimatization or artificial acclimation heat HA is the most efficacious method to defend homeostasis at rest and during exercise in hot environments Our project will determine if three weeks of heat acclimation maintenance HAM further potentiates exercise performance in the heat than exercise performance measured after 10 days of HA in females
Justification Female participation in arduous occupations and professional sport is increasing Presently a paucity of data regarding the female response to heat acclimation exist Findings from this study will help females undertake effective and efficient strategies to mitigate thermal strain
Research design This is an experimental trial with a treatment and a control group VO2max plasma volume PV core temperature and cardiac output will be measured pre- mid- and post-intervention Participants will complete 10 sessions of HA over two weeks Participants will then undergo three weeks of HAM with three heat sessions per week A heat performance test will be completed pre- mid- and post-intervention to examine performance changes A control group will complete the same test schedule but will not perform any HA or HAM
Statistical analysis Sample size will be 8 females in the experimental and 6 females in the control group Data will be analyzed for normality using the Shapiro-Wilk test Descriptive statistics will be presented as the mean and standard deviation Statistical significance will be determined at P 005 A two-way repeated measure ANOVA will be used to measure differences between groups and hemodynamic cardiovascular and performance variable differences pre- and post-HA and pre- post-HAM If significant effects are present these will be followed by a post-hoc Tukeys test Pearsons r correlations two-tailed will be conducted between VO2max and intravascular volumes and heat performance test outcome
Justification Female participation in arduous occupations and professional sport is increasing Presently a paucity of data regarding the female response to heat acclimation exist Findings from this study will help females undertake effective and efficient strategies to mitigate thermal strain
Research design This is an experimental trial with a treatment and a control group VO2max plasma volume PV core temperature and cardiac output will be measured pre- mid- and post-intervention Participants will complete 10 sessions of HA over two weeks Participants will then undergo three weeks of HAM with three heat sessions per week A heat performance test will be completed pre- mid- and post-intervention to examine performance changes A control group will complete the same test schedule but will not perform any HA or HAM
Statistical analysis Sample size will be 8 females in the experimental and 6 females in the control group Data will be analyzed for normality using the Shapiro-Wilk test Descriptive statistics will be presented as the mean and standard deviation Statistical significance will be determined at P 005 A two-way repeated measure ANOVA will be used to measure differences between groups and hemodynamic cardiovascular and performance variable differences pre- and post-HA and pre- post-HAM If significant effects are present these will be followed by a post-hoc Tukeys test Pearsons r correlations two-tailed will be conducted between VO2max and intravascular volumes and heat performance test outcome
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None