Ignite Creation Date:
2024-10-26 @ 3:37 PM
Last Modification Date:
2024-10-26 @ 3:37 PM
Study NCT ID:
NCT06553391
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-07-12
Brief Title:
Heart Rhythm Changes in Patients With Atrial Fibrillation After Cardiopulmonary Bypass a Retrospective Analysis
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Heart Rhythm Changes in Patients With Atrial Fibrillation After Cardiopulmonary Bypass a Retrospective Analysis
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this observational study is to learn about the lthe effect of the tetralogy of medication regimen on intraoperative cardioversion in patients with persistent AF The main question it aims to answer is
Does the regimen improve the success rate of cardioversion in patients with persistent AF during cardiac surgery The treatment protocol commences with the administration of amiodarone followed by the administration of either all or a portion of the subsequent medications aminophylline ephedrine and isoproterenol
This observational cohort study was conducted at the Chinese Academy of Medical Sciences Fuwai Shenzhen Hospital using the electronic medical record database from March 7 2023 to January 1 2025 Patients diagnosed with atrial fibrillation who underwent cardiac surgery between June 1 2000 and January 31 2023 were included in the study
Does the regimen improve the success rate of cardioversion in patients with persistent AF during cardiac surgery The treatment protocol commences with the administration of amiodarone followed by the administration of either all or a portion of the subsequent medications aminophylline ephedrine and isoproterenol
This observational cohort study was conducted at the Chinese Academy of Medical Sciences Fuwai Shenzhen Hospital using the electronic medical record database from March 7 2023 to January 1 2025 Patients diagnosed with atrial fibrillation who underwent cardiac surgery between June 1 2000 and January 31 2023 were included in the study
Detailed Description:
Background Most patients with atrial fibrillation AF continue to experience AF following cardiac surgery which is not conducive to postoperative circulatory stability Intraoperative active cardioversion has rarely studied due to uncertainty regarding the efficacy of pharmacological cardioversion and the recurrence rate of AF in patients with persistent AF
Objective To assess the effect of the tetralogy of medication regimen on intraoperative cardioversion in patients with persistent AF
Methods This observational cohort study was conducted at the Chinese Academy of Medical Sciences Fuwai Shenzhen Hospital using the electronic medical record database from March 7 2023 to January 1 2025 Patients diagnosed with AF who underwent cardiac surgery between June 1 2000 and January 31 2023 were included in the study These patients undergoing pharmacological cardioversion during surgery were matched with untreated patients in a 11 ratio based on age sex weight diagnosis beta blocker and digoxin usage indicators from cardiac ultrasound and blood gas analysis The treatment protocol commences with the administration of amiodarone followed by the administration of either all or a portion of the subsequent medications aminophylline ephedrine and isoproterenol The choice between these drugs depends on the patients blood pressure and heart rate The incidence of cardioversion in patients who underwent the tetralogy of medication regimen approach was compared with that of untreated patients Data analyses took place from March 1 2024
Objective To assess the effect of the tetralogy of medication regimen on intraoperative cardioversion in patients with persistent AF
Methods This observational cohort study was conducted at the Chinese Academy of Medical Sciences Fuwai Shenzhen Hospital using the electronic medical record database from March 7 2023 to January 1 2025 Patients diagnosed with AF who underwent cardiac surgery between June 1 2000 and January 31 2023 were included in the study These patients undergoing pharmacological cardioversion during surgery were matched with untreated patients in a 11 ratio based on age sex weight diagnosis beta blocker and digoxin usage indicators from cardiac ultrasound and blood gas analysis The treatment protocol commences with the administration of amiodarone followed by the administration of either all or a portion of the subsequent medications aminophylline ephedrine and isoproterenol The choice between these drugs depends on the patients blood pressure and heart rate The incidence of cardioversion in patients who underwent the tetralogy of medication regimen approach was compared with that of untreated patients Data analyses took place from March 1 2024
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None