Ignite Creation Date:
2024-10-26 @ 3:37 PM
Last Modification Date:
2024-10-26 @ 3:37 PM
Study NCT ID:
NCT06553755
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
None
First Post:
2024-08-12
Brief Title:
Multidimensional Recovery Patterns and Prognostic Factors After Stroke
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Unraveling the Multidimensional Functional Recovery Patterns and Prognostic Factors in Post-Discharged Stroke Survivors A Retrospective Study
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study aims to compare the 1-year recovery trajectories of multidimensional functional recovery among stroke survivors after discharge from acute care
To address this purpose a retrospective analysis will be conducted using clinical data from two independent cohorts derived from previously published prospective observational studies The study will conduct generalized estimating equations and mixed-effects regression models to assess differences in recovery trends among stroke subgroups
The findings will provide detailed profiles of longitudinal changes in functional outcomes one year after discharge from acute care These results will clarify how stroke subtypes influence long-term functional outcomes and will guide the development of targeted interventions
To address this purpose a retrospective analysis will be conducted using clinical data from two independent cohorts derived from previously published prospective observational studies The study will conduct generalized estimating equations and mixed-effects regression models to assess differences in recovery trends among stroke subgroups
The findings will provide detailed profiles of longitudinal changes in functional outcomes one year after discharge from acute care These results will clarify how stroke subtypes influence long-term functional outcomes and will guide the development of targeted interventions
Detailed Description:
Different stroke types have unique pathophysiological mechanisms that likely affect various recovery outcomes Understanding stroke-subtype-specific functional recovery and outcomes is crucial for effective rehabilitation and discharge planning However current evidence does not fully reveal how functional outcomes differ by stroke subtype leaving gaps in our understanding of how these differences impact post-stroke recovery Identifying the specific recovery patterns and prognostic factors associated with each stroke subtype can enhance personalized rehabilitation strategies and improve patient care
To address this purpose a retrospective study utilizing clinical data from two independent cohorts recruited from collaborative hospitals in Northern Taiwan between 2016 and 2018 will be implemented The study will employ several outcome measures including the Participation Measure-3 Domains 4 Dimensions PM-3D4D the Activity Measure for Post-Acute Care AM-PAC the modified Rankin Scale mRS and other standardized assessment tools Participants will be assessed at four time points at discharge from acute care T1 and at 3 months T2 6 months T3 and 12 months T4 post-discharge Data analysis will use generalized estimating equations and mixed-effects regression models to evaluate differences in recovery trends among stroke subgroups
The findings will offer comprehensive insights into the progression of various functional outcomes of specific stroke subtypes over the course of one year following discharge The study will also identify factors associated with long-term functional outcomes and investigate how those factors impact the trend of functional recovery These results will demonstrate the association of stroke subtypes and long-term functional outcomes facilitating the development of targeted interventions
To address this purpose a retrospective study utilizing clinical data from two independent cohorts recruited from collaborative hospitals in Northern Taiwan between 2016 and 2018 will be implemented The study will employ several outcome measures including the Participation Measure-3 Domains 4 Dimensions PM-3D4D the Activity Measure for Post-Acute Care AM-PAC the modified Rankin Scale mRS and other standardized assessment tools Participants will be assessed at four time points at discharge from acute care T1 and at 3 months T2 6 months T3 and 12 months T4 post-discharge Data analysis will use generalized estimating equations and mixed-effects regression models to evaluate differences in recovery trends among stroke subgroups
The findings will offer comprehensive insights into the progression of various functional outcomes of specific stroke subtypes over the course of one year following discharge The study will also identify factors associated with long-term functional outcomes and investigate how those factors impact the trend of functional recovery These results will demonstrate the association of stroke subtypes and long-term functional outcomes facilitating the development of targeted interventions
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None