Ignite Creation Date:
2024-10-26 @ 3:37 PM
Last Modification Date:
2024-10-26 @ 3:37 PM
Study NCT ID:
NCT06554405
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-08-12
Brief Title:
Bilateral vs Unilateral Neuromobilization in Carpal Tunnel Syndrome
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Examining the Effects of Bilateral Neuromobilization in Patients With Carpal Tunnel Syndrome Comparison Study With Unilateral Application
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study aims to investigate whether bilateral both extremities together neuromobilization is superior to unilateral only the affected side neuromobilization in individuals diagnosed with Carpal Tunnel Syndrome
Detailed Description:
Carpal Tunnel Syndrome CTS is defined as an upper extremity nerve entrapment resulting from the compression of the median nerve at the wrist level It is the most common entrapment neuropathy Patients with CTS experience numbness tingling and pain in the hand which can sometimes extend to the arm along with hand weakness and thenar atrophy These symptoms typically worsen after hand use and at night While clinical findings are absent in the early stages of the disease sensory and strength loss is observed in the areas innervated by the median nerve in advanced stages
The pathophysiology of CTS includes hypertrophic changes in the synovial tissue of the flexor tendon connective tissue changes in the median nerve conduction disturbances and increased pressure in the carpal tunnel
Treatment is tailored to the patients symptoms Conservative treatment is preferred in mild to moderate stages while surgical intervention may be necessary in advanced stages All patients should receive education on ergonomics aimed at reducing symptoms in daily life
Conservative treatment for CTS includes nerve mobilization techniques the use of orthoses to maintain the wrist in a neutral position electrotherapy ESWT laser manual therapy kinesiotaping corticosteroid and platelet-rich plasma PRP injections and anti-inflammatory medications Patients who do not respond to conservative treatment are referred for surgery
Neural structures are capable of tolerating significant tension and compression forces encountered during daily activities and sports This capability is due to the connective tissue sheath surrounding the nerve
The musculoskeletal system creates an environment that surrounds the nervous system and its movements affect peripheral nerves With the excursion sliding movement compression on the peripheral nerve decreases Clinical neuromobilization is a manual therapy method that integrates the mechanics and physiology of the nervous system with musculoskeletal function Neuromobilization NM aims to balance the relationship between neural tissues and surrounding mechanical tissues thereby regulating optimal physiological functions
The aim of using neuromobilization exercises with sliding techniques in nerve entrapments is to increase axonal transport and improve nerve conduction It has been suggested that these exercises can reduce pressure within the nerve improve its blood supply and thus contribute to nerve regeneration Recent studies in the literature report that neuromobilization exercises have supportive effects in pain improvement reduction of distal latency time and increased pinch strength A systematic review indicated these effects as pain improvement lowering the pain threshold improving function and avoiding surgery It was stated that neuromobilization exercises added to the CTS treatment program accelerate the rehabilitation process and enhance recovery
Although there are studies in the literature proving the superiority of neuromobilization over other treatment methods the number of studies investigating the application of neuromobilization to the unaffected side is limited Considering that the connective tissue sheaths surrounding peripheral nerves in both upper extremities are connected via the central nervous system it is hypothesized that neuromobilization applied to the unaffected side or bilaterally might be more effective on the symptomatic side compared to unilateral application However studies that consider this connection and include the unaffected side in treatment are significantly lacking
The pathophysiology of CTS includes hypertrophic changes in the synovial tissue of the flexor tendon connective tissue changes in the median nerve conduction disturbances and increased pressure in the carpal tunnel
Treatment is tailored to the patients symptoms Conservative treatment is preferred in mild to moderate stages while surgical intervention may be necessary in advanced stages All patients should receive education on ergonomics aimed at reducing symptoms in daily life
Conservative treatment for CTS includes nerve mobilization techniques the use of orthoses to maintain the wrist in a neutral position electrotherapy ESWT laser manual therapy kinesiotaping corticosteroid and platelet-rich plasma PRP injections and anti-inflammatory medications Patients who do not respond to conservative treatment are referred for surgery
Neural structures are capable of tolerating significant tension and compression forces encountered during daily activities and sports This capability is due to the connective tissue sheath surrounding the nerve
The musculoskeletal system creates an environment that surrounds the nervous system and its movements affect peripheral nerves With the excursion sliding movement compression on the peripheral nerve decreases Clinical neuromobilization is a manual therapy method that integrates the mechanics and physiology of the nervous system with musculoskeletal function Neuromobilization NM aims to balance the relationship between neural tissues and surrounding mechanical tissues thereby regulating optimal physiological functions
The aim of using neuromobilization exercises with sliding techniques in nerve entrapments is to increase axonal transport and improve nerve conduction It has been suggested that these exercises can reduce pressure within the nerve improve its blood supply and thus contribute to nerve regeneration Recent studies in the literature report that neuromobilization exercises have supportive effects in pain improvement reduction of distal latency time and increased pinch strength A systematic review indicated these effects as pain improvement lowering the pain threshold improving function and avoiding surgery It was stated that neuromobilization exercises added to the CTS treatment program accelerate the rehabilitation process and enhance recovery
Although there are studies in the literature proving the superiority of neuromobilization over other treatment methods the number of studies investigating the application of neuromobilization to the unaffected side is limited Considering that the connective tissue sheaths surrounding peripheral nerves in both upper extremities are connected via the central nervous system it is hypothesized that neuromobilization applied to the unaffected side or bilaterally might be more effective on the symptomatic side compared to unilateral application However studies that consider this connection and include the unaffected side in treatment are significantly lacking
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None