Ignite Creation Date:
2024-10-26 @ 3:37 PM
Last Modification Date:
2024-10-26 @ 3:37 PM
Study NCT ID:
NCT06554951
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-08-09
Brief Title:
Study of Extracellular Vesicles EV in Patients Undergoing CAR-T Cell Therapies
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Studio Delle Vescicole Extracellulari EV in Pazienti Sottoposti a Terapie Con Cellule CAR-T
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
CARE_24
Brief Summary:
Patients with refractoryrelapse hematologic oncology disease may benefit from innovative therapy such as Car-T cells Factors strongly predictive of outcome and response are unknown Extracellular vesicles are recognized as a mode of intercellular communication and are reminiscent of the cell of origin They are currently candidates to be biomarkers for this biomarker of phenomena occurring in tissues The working hypothesis is that they may be predictive of outcome and toxicity as some preliminary data have suggested
Therefore the aim of the study concerns I dentification of potential CAR-EV biomarkers associated with neurological toxicity after infusion of CAR-T cells
Therefore the aim of the study concerns I dentification of potential CAR-EV biomarkers associated with neurological toxicity after infusion of CAR-T cells
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None