Ignite Creation Date:
2024-10-26 @ 3:38 PM
Last Modification Date:
2024-10-26 @ 3:38 PM
Study NCT ID:
NCT06556823
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-08-13
Brief Title:
Contralateral Leg Neuro-dynamic and Spine Mobilization With Leg Movement in Patients With Sciatica
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Comparison of Contralateral Leg Neuro-dynamic Technique and Spine Mobilization With Leg Movement in Diabetic and Non-diabetic Patients With Sciatica
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this randomized clinical trial is to find the comparison of CLNDT and SMWLM technique in diabetic and non-diabetic sciatica patients on reducing back pain and improving range of motion of knee
Detailed Description:
Sciatica is the broad term describe as radicular pain or paresthesia that originate from low back and radiate along sciatic nerve or with associated lumbosacral nerve root Sciatica may occur unilaterally or bilaterally with or without lower extremity pain People with sciatica describe sharp aching and radiating leg pain It may cause neurological problem such as weakness numbness or hypo-reflexes and in some cases bladder dysfunction may be present Pain and discomfort in sciatica affect daily life activities such as walking bending and running adversely which affect the quality of life
Diabetes mellitus is a chronic hyperglycemic multisystem disorder which is characterized by either genetic or metabolic dysfunction It is further classified into two categories type 1 diabetes mellitus T1DM which is genetic disorder that prevents the pancreatic beta cells to secrete insulin either due to destruction or reduced number of pancreatic beta cells and type 2 diabetes mellitus T2DM is a metabolic disorder in which peripheral insulin receptors of the body become resistant to insulin The underlying pathophysiology of diabetes and lumbar spine disorders shows a strong association between lumbar degeneration and type 2 diabetes as there is increasing end product of toxic glycation Expression of MMP-2 related to degradation of extracellular matrix and hyperglycemia induced inflammation of disc although these changes were observed in animals as in human there is still some lacking about its pathophysiology
Contralateral leg neuro-dynamic technique was introduced by Shacklock on Maitland concept of slump test that with in slump test position contralateral leg pain is reduced by maintaining this position This technique is use to reduced pain and increase ROM in sciatica patients Spinal Mobilization with leg movement was developed by Brain Mulligan in this technique continuous lateral glides was applied on spinous process and performing actively or passively leg movement this technique is also use for sciatica patients to reduce pain and increase ROM
The Rational of present study is to determine which technique CLNDT or SMWLM is more effective than other for Pain ROM and disability in diabetic and non- diabetic patients with sciatica It will also determine effect of HbA1C level on pain ROM and Disability on CLNDT and SMWLM techniques in Diabetic patients with sciatica
Diabetes mellitus is a chronic hyperglycemic multisystem disorder which is characterized by either genetic or metabolic dysfunction It is further classified into two categories type 1 diabetes mellitus T1DM which is genetic disorder that prevents the pancreatic beta cells to secrete insulin either due to destruction or reduced number of pancreatic beta cells and type 2 diabetes mellitus T2DM is a metabolic disorder in which peripheral insulin receptors of the body become resistant to insulin The underlying pathophysiology of diabetes and lumbar spine disorders shows a strong association between lumbar degeneration and type 2 diabetes as there is increasing end product of toxic glycation Expression of MMP-2 related to degradation of extracellular matrix and hyperglycemia induced inflammation of disc although these changes were observed in animals as in human there is still some lacking about its pathophysiology
Contralateral leg neuro-dynamic technique was introduced by Shacklock on Maitland concept of slump test that with in slump test position contralateral leg pain is reduced by maintaining this position This technique is use to reduced pain and increase ROM in sciatica patients Spinal Mobilization with leg movement was developed by Brain Mulligan in this technique continuous lateral glides was applied on spinous process and performing actively or passively leg movement this technique is also use for sciatica patients to reduce pain and increase ROM
The Rational of present study is to determine which technique CLNDT or SMWLM is more effective than other for Pain ROM and disability in diabetic and non- diabetic patients with sciatica It will also determine effect of HbA1C level on pain ROM and Disability on CLNDT and SMWLM techniques in Diabetic patients with sciatica
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None