Ignite Creation Date:
2024-10-26 @ 3:38 PM
Last Modification Date:
2024-10-26 @ 3:38 PM
Study NCT ID:
NCT06561789
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-08-10
Brief Title:
Remineralization Effect of βTricalcium Phosphate Nanoparticles Versus FunctionalizedβTricalcium Phosphate Nanoparticles
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Efficacy of Remineralizing Potential of β-Tricalcium Phosphate Nanoparticles Versus Functionalizedβ-Tricalcium Phosphate Nanoparticles
Status:
COMPLETED
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The study collects Sixty non carious sound human permanent premolars from Tanta Universitys maxillofacial surgery department The teeth are cleaned and prepared and randomly assigned into four groups The specimens are analyzed using an EDX analysis scanning electron microscope and surface micro-hardness is determined using a Digital Display Vickers Micro-hardness Tester
Detailed Description:
The study involves collecting Sixty non carious sound human permanent premolars from an outpatient clinic at Tanta Universitys maxillofacial surgery department The teeth are selected for their absence of caries hypocalcification restoration fracture fluorosis and cracks The teeth are cleaned and prepared for the study including demineralization and artificial incipient enamel carious lesion preparation The teeth are randomly assigned into four groups functionalized Nano ᵦ tricalcium phosphate particles Nano ᵦ tricalcium phosphate particles sodium fluoride mouth wash and artificial saliva The pH of all groups is adjusted at 7 The specimens are treated in a daily pH cycling regime with daily solution replacements The specimens are then dried and analyzed using an Energy Dispersive X-Ray EDX analysis scanning electron microscope The element content distribution of calcium and phosphorus elements is measured and the specimens are evaluated at base line after demineralization and after 2 4 and 6 weeks Surface micro-hardness is determined using a Digital Display Vickers Micro-hardness Tester
Data will be collected presented and statistically analyzed using SPSS software package system using ANOVA at a significance level of 005
Data will be collected presented and statistically analyzed using SPSS software package system using ANOVA at a significance level of 005
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None