Ignite Creation Date:
2024-10-26 @ 3:38 PM
Last Modification Date:
2024-10-26 @ 3:38 PM
Study NCT ID:
NCT06562504
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-08-15
Brief Title:
Temporal Memory in Schizophrenic Patients
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Transcranial Electrical Stimulation Combined With Interim Testing Promotes Temporal Memory in Patients With Schizophrenia
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Temporal order memory deficits are a central feature of cognitive abnormalities in schizophrenia The dorsolateral prefrontal cortex contributes to the extraction of temporal contextual information Transcranial direct current stimulation tDCS and interim testing have been shown to be external techniques that can improve temporal order memory deficits in schizophrenia patients Transcranial alternating current stimulation tACS can also improve cognitive functioning in patients with schizophrenia This study intends to investigate the learning effects of temporal order memory under two learning strategies during tDCS targeting the left dorsolateral prefrontal cortex L-DLPFC and transcranial direct current stimulation tDCS interventions in patients with schizophrenia to investigate whether it can promote the retention of temporal order memory in patients and to compare the differences in the effects of the two intervention modalities
This study was planned to recruit 75 patients diagnosed with schizophrenia from the hospital
A single online tDCS 2 mA 20 min and tACS 15 mA 20 min theta rhythm intervention was conducted during which participants performed a temporal-sequence memory task for visual pictures and test scores were compared for each stimulus type on an intermediate test and repetition of the two strategies of learning
This study was planned to recruit 75 patients diagnosed with schizophrenia from the hospital
A single online tDCS 2 mA 20 min and tACS 15 mA 20 min theta rhythm intervention was conducted during which participants performed a temporal-sequence memory task for visual pictures and test scores were compared for each stimulus type on an intermediate test and repetition of the two strategies of learning
Detailed Description:
Treatment was conducted by two examiners and participants memory levels were tested before the start of the experiment using a flanker task and a numerical breadth task as baseline tests The experimental procedure was divided into a learning phase in which participants memorized the sequence of pictures and a testing phase in which participants were required to recall a picture presented after the probe item Participants were randomly assigned in parallel to each stimulus type and learning strategy with 25 receiving tdcs anodized stimuli 25 receiving sham stimuli and another 25 receiving tacs stimuli And participants inhibitory control continued to be tested using the flanker task before and after the stimuli for pre- and post-intervention comparisons
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None