Ignite Creation Date:
2024-10-26 @ 3:38 PM
Last Modification Date:
2024-10-26 @ 3:38 PM
Study NCT ID:
NCT06563219
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-08-17
Brief Title:
Predicting 28-Day Mortality in Subarachnoid Hemorrhage
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Comparative Analysis of Traditional Clinical Scores and Combined Grading Systems in Predicting 28-Day Mortality in Non-Traumatic Subarachnoid Hemorrhage
Status:
COMPLETED
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
SAHstdy
Brief Summary:
The investigators investigated the predictive ability of clinical and radiological scores including the Glasgow coma scale GCS Hunt-Hess World Federation of Neurological Surgeons WFNS and modified Fisher scales as well as combined clinical scores such as the VASOGRADE and Ogilvy-Carter rating scales for 28-day mortality in patients presenting to the emergency department ED with non-traumatic subarachnoid hemorrhage SAH Specifically we tested the hypothesis that combined clinical scores are more reliable and superior to non-combined clinical and radiological scores in predicting 28-day mortality in non-traumatic SAH
Detailed Description:
Patients were divided into survivors and non-survivors with surviving patients further categorized as either mobile or immobile based on the Glasgow outcome scale Accordingly patients who were dependent on daily support or in a coma were classified as immobile whereas patients who had returned to normal life or were independent in their daily activities were classified as mobile The demographic age and sex comorbidities hypertension diabetes mellitus DM andor coronary artery disease CAD vital signs systolic blood pressure heart rate respiratory rate and peripheral capillary oxygen saturation sPO2 and clinical assessment tools GCS Hunt Hess WFNS modified Fisher VASOGRADE and Ogilvy-Carter rating scales on admission were compared between the groups to identify factors associated with 28-day mortality and neurological survival Independent predictors of mortality were determined by multivariate logistic regression analysis of variables demographic characteristics clinical characteristics and trauma scores that differed significantly between survivors and non-survivors An area under the curve AUC analysis was then conducted to identify which trauma score is the most reliable and superior predictor of mortality
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None