Ignite Creation Date:
2024-10-26 @ 3:38 PM
Last Modification Date:
2024-10-26 @ 3:38 PM
Study NCT ID:
NCT06571721
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-08-23
Brief Title:
The Effects of Topical Almond Oil and Tretinoin on Facial Wrinkles
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Prospective Double-Blinded Randomized Study of Topical Almond Oil and Tretinoin on Facial Wrinkles
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Investigate the topical use of almond oil almond oil augmented with 05 vitamin E 0025 tretinoin oil augmented with castor oil on the appearance of facial fine lines and wrinkles pigmentation hydration trans-epidermal water loss and sebum excretion rate
Detailed Description:
The natural cosmetic market is a multi-billion dollar industry Nutraceuticals and food-based cosmetics are a growing trend within dermatology Almonds are a rich dietary source of a range of fatty acids phytochemical polyphenols and antioxidants Our previous study was a double blinded study that compared almond consumption interventions to a calorie matched intervention over 16 weeks The study determined that that there was a statistically significant 841 improvement in wrinkle severity in the women that received almond supplementation This proposal aims to now understand how the topical application of almond oil may influence the appearance of wrinkles and facial tone in post-menopausal women Almond oil is rich in fatty acids and alpha-tocopherol Tocopherol inhibits melanogenesis in melanocytes and topical alpha tocopherol has been shown to improve skin antioxidants and hyperpigmentation A challenge of almond oil is that it is prone to oxidation due to its high unsaturated fatty acid concentrations However tocopherol has also been shown to improve almond oil stability
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None