Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06574464
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-08-25
Brief Title:
The BIG Score and In-Hospital Trauma Mortality
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Predicting Mortality in Adults Hospitalized With Multiple Trauma Can the BIG Score Estimate Risk
Status:
COMPLETED
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
BIGstd
Brief Summary:
This study investigated the efficacy and reliability of the BIG score calculated based on the base deficit BD International Normalized Ratio INR and Glasgow coma scale GCS in comparison with the GCS Revised trauma score RTS and Injury Severity Score ISS for predicting in-hospital mortality in adults with multiple-trauma presenting to the emergency department ED
Detailed Description:
This retrospective observational single-center study included 563 consecutive adults 18 years old with multiple trauma who were admitted to our emergency department and hospitalized between January 2022 and December 2023 We assessed patient demographics age and sex vital signs on admission systolic blood pressure SBP mmHg heart rate HR beatsmin respiratory rate RR breathsmin and peripheral oxygen saturation SpO2 complaints and symptoms on admission anatomic region of injury type of trauma blunt or penetrating mechanism of injury BD measured in blood gases INR trauma scoring systems eg GCS RTS ISS and BIG score and clinical outcomes discharge hospitalization or death The study cohort was divided into survivors and non-survivors Survivors were defined as patients who were still alive after 28 days while non-survivors had passed away within that time The demographics clinical characteristics and trauma scoring systems were compared between survivors and non-survivors to determine the prognosis of patients with multiple trauma Independent predictors of mortality were determined by multivariate logistic regression analysis of variables demographic characteristics clinical characteristics and trauma scores that differed significantly between survivors and non-survivors Receiver operating characteristic ROC curve analysis was performed to establish cut-off values for the GCS RTS ISS and BIG score and then to assess the sensitivity and specificity of these scoring systems in terms of predicting in-hospital mortality
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None