Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06574659
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-07-17
Brief Title:
Noninvasive Ventilation Breathing Test Guiding Weaning in Patients With Acute Hypoxic Respiratory Failure
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Noninvasive Ventilation Breathing Test Guiding Sequential Invasive and Noninvasive Ventilation Weaning of Patients With Acute Hypoxic Respiratory Failure a Randomized Multicenter Controlled Trial
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
SBT as a routine extubation strategy for invasive mechanical ventilation has been widely recognized However in recent years studies have found that SBT may lead to delayed extubation which has been confirmed in COPD patients but has not yet been widely accepted in patients with acute hypoxic respiratory failure Both invasive mechanical ventilation and non-invasive mechanical ventilation are positive pressure ventilation with the essential difference being the human-machine interface The safe inspiratory pressure for non-invasive mechanical ventilation should not exceed 20cmH2O 1cmH2O0098 kPa If the cause of respiratory failure is relieved or removed respiratory function improves and the patient has good airway protection ability and can tolerate non-invasive ventilation the endotracheal tube can be removed as soon as possible to switch to non-invasive mechanical ventilation thereby shortening the time of invasive mechanical ventilation and reducing the risk of complications This study trial aims to identify the timing of early extubation sequential non-invasive mechanical ventilation in patients with acute hypoxic respiratory failure through non-invasive ventilation breathing tests providing a basis for updating the process of invasive mechanical ventilation extubation
Detailed Description:
All the patients included will be randomly assigned to receive Non Invasive Ventilation Breathing Test protocol or SBT protocol
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None