Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06575101
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-08-23
Brief Title:
Resting Energy Expenditure and Substrate Consumption in Cardiac Arrest Patients Under Target Temperature Management
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Resting Energy Expenditure and Substrate Consumption in Cardiac Arrest Patients Under Target Temperature Management
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study is a single-center prospective observational study According to the sample size formula an estimated 40 cases should be collected all of whom are from the emergency intensive care unit After successful cardiopulmonary resuscitation the enrolled patients will be transferred to the emergency intensive care unit for further standardized target temperature management TTM They will be divided into 33 C hypothermia group and 36 C hypothermia group according to the patients core body temperature The baseline data of the patients will be collected at the beginning After admission to the hospital they were fasted within 24 hours to reach the target temperature and then 20kcalkgd parenteral nutrition will be given At selected time points T0 the initial time point before TTM T1 the core temperature was reduced to 33 C or 36 C T2-T4 33 C or 36 C was maintained for 24h 48h 72h T5 the end of rewarming Tend the last REE measurement before discharge or death various observation indicators will be collected including resting energy expenditure REE glucose oxidation rate fat oxidation rate protein oxidation rate and metabolism of three major nutrients Proportion Neurological outcomes were followed up 28 days after onset according to the Cerebral Performance Categories CPC score
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None