Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06576687
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-08-26
Brief Title:
Neurophysiology of Ankle Instability
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Understanding the Neurophysiology of Ankle Instability to Improve Rehabilitation Outcomes
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this study is to determine functional and neurophysiological differences between subgroups of chronic ankle instability CAI to allow for the development of evidence-based rehabilitation which may improve patient outcomes The main questions are1 determine the differences among CAI subgroups on performance of a traditional side-hop test and neurocognitive hop test 2 determine the differences in neurophysiological response and motor control between chronic ankle instability subgroups during a lower limb and an ankle specific task and 3 determine the underlying neurophysiological effects of a 4-week neurocognitively enhanced balance training protocol among CAI subgroups
Detailed Description:
Chronic ankle instability CAI is a common debilitating orthopedic condition that disrupts physical function and decreases quality of life Chronic ankle instability is heterogenous and can manifest as mechanical ligamentous laxity perceived disability often referred to as functional instability or a combination of the two However clinicians and researchers most often combine all chronic ankle instability patients without considering these subgroups which may account for the poor recovery and recurrent nature of this pathology Neurocognitive and neurophysiologic discrepancies may explain the different subgroups observed in this population however technological limitations have previously limited this assessment The objective of this research is to determine functional and neurophysiological differences between subgroups of CAI to allow for development of evidence-based rehabilitation which may improve patient outcomes To accomplish this the aims of this study are 1 determine the differences among CAI subgroups on performance of a traditional side-hop test and neurocognitive hop test 2 determine differences in neurophysiological response and motor control between CAI subgroups during a lower limb and an ankle specific task and 3 determine the underlying neurophysiological effects of a 4-week neurocognitively enhanced balance training protocol among CAI subgroups This study hypothesizes functional performance will be similar between subgroups during a traditional side-hop test but those with functional instability without mechanical laxity will perform worse during a choice-reaction hop test compared to those with mechanical ankle instability It also hypothesizes individuals with functional ankle instability will demonstrate greater cortical activation during the research tasks and after a 4-week balance training protocol compared to individuals with mechanical ankle instability To assess these aims participants with CAI who present with functional ankle instability as well as with mechanical ankle instability will perform a series of hop tests single limb balance test a force control test a neurocognitive assessment and 4-weeks of neurocognitive balance training Time to complete each of the hop tests cortical activation during the balance and force control tasks and neurocognitive performance will be assessed to determine differences in performance and neurological function among subgroups of CAI Therefore the long-term objective of this research is to determine the underlying neurologic neurophysiologic and motor control mechanisms underpinning CAI to improve evidence-based decision making across patients with chronic ankle instability
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None