Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06576791
Status:
COMPLETED
Last Update Posted:
None
First Post:
2022-09-19
Brief Title:
Urethral Rotation Angles and Foot Pronation Mechanical Changes in Postmenopausal Women
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Urethral Rotation Angles and Foot Pronation Mechanical Changes in Postmenopausal Women
Status:
COMPLETED
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Stress urinary incontinence SUI occur secondary to increased intra abdominal pressure that directed the researchers to study the mechanical changes in urethra and bladder that associated with it However these urethral mechanical changes may be related to other mechanical changes in the body
Detailed Description:
Stress urinary incontinence SUI affects about 26 of women between 30 and 59 years of age It is the sudden involuntary urine leakage secondary to increased intra abdominal pressure related to physical activities as laughing sneezing straining coughing or exercising There are two common mechanisms for SUI urethral hypermobility due to loss of support of the bladder neck and urethra affected by increased intra-abdominal pressure and weakness of the urinary sphincter that may result from trauma repeated urogynaecological surgeries neurological disease ageing or diseases leading to systemic muscular atrophy SUI is the most common pelvic floor dysfunction linked to the vaginal delivery However the prevalence of stress incontinence peaks occurs in the fifth decade of life and all types of incontinence are commonly occurring with ageing and obesity
Urethral hypermobility means that the proximal part of the urethra may exhibit a rotational movement in a postero-inferior direction And it was diagnosed when the urethra rotated during strain over 30 from its resting axis Urethral rotation angles may assist in both assessment and diagnosis of patients with SUI which may in turn decreases requires for any other investigations The ultrasonography assessment of the angle of inclination α angle the angle between the axis of the proximal urethra and the central axis of the symphysis pubis and posterior urethrovesical angle β angle the angle between the proximal urethra and the posterior vesical wall has been investigated by several researchers However recently transperineal ultrasonography is a practical reliable non-invasive and comfortable method for evaluation of SUI Additionally it has the advantage of dynamic evaluation during the Valsalva maneuver
Urinary sphincter composed of internal urethral sphincter that is predominantly smooth muscle without voluntary control and the external urethral sphincter and pelvic floor muscles PFMs that are predominantly striated muscle with voluntary control During activities the PFMs contract to prevent the leakage of urine in addition they play a significant role in trunk stabilization through its connections with abdominal muscles diaphragm and gluteus by myofascial continuity Contractions of PFMs lead to activation of gluteal muscles especially the levator ani through their connection by the fossa ischioanalis Additionally rotators mainly the internal obturator and piriformis muscles are important for maintaining pelvic stability and PFM functionality Moreover the tension of the rotator cuff and gluteal muscles is also primarily determined by position of the foot So the tension of PFM may affect the tension and functioning of the rotators and gluteal muscles thus influencing the biomechanics and position of whole lower limb even the foot position
Urethral hypermobility means that the proximal part of the urethra may exhibit a rotational movement in a postero-inferior direction And it was diagnosed when the urethra rotated during strain over 30 from its resting axis Urethral rotation angles may assist in both assessment and diagnosis of patients with SUI which may in turn decreases requires for any other investigations The ultrasonography assessment of the angle of inclination α angle the angle between the axis of the proximal urethra and the central axis of the symphysis pubis and posterior urethrovesical angle β angle the angle between the proximal urethra and the posterior vesical wall has been investigated by several researchers However recently transperineal ultrasonography is a practical reliable non-invasive and comfortable method for evaluation of SUI Additionally it has the advantage of dynamic evaluation during the Valsalva maneuver
Urinary sphincter composed of internal urethral sphincter that is predominantly smooth muscle without voluntary control and the external urethral sphincter and pelvic floor muscles PFMs that are predominantly striated muscle with voluntary control During activities the PFMs contract to prevent the leakage of urine in addition they play a significant role in trunk stabilization through its connections with abdominal muscles diaphragm and gluteus by myofascial continuity Contractions of PFMs lead to activation of gluteal muscles especially the levator ani through their connection by the fossa ischioanalis Additionally rotators mainly the internal obturator and piriformis muscles are important for maintaining pelvic stability and PFM functionality Moreover the tension of the rotator cuff and gluteal muscles is also primarily determined by position of the foot So the tension of PFM may affect the tension and functioning of the rotators and gluteal muscles thus influencing the biomechanics and position of whole lower limb even the foot position
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None