Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06579170
Status:
ENROLLING_BY_INVITATION
Last Update Posted:
None
First Post:
2024-08-28
Brief Title:
Burden of Recreational Water Illness Due to Exposure to Cyanobacteria and Their Toxins in Freshwater Beaches in Canada
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Burden of Recreational Water Illness Due to Exposure to Cyanobacteria and Their Toxins in Freshwater Beaches in Canada a Prospective Cohort Study
Status:
ENROLLING_BY_INVITATION
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Swimming and other recreational water activities at public beaches are increasingly popular leisure activities among Canadians However harmful algal blooms caused by blue-green algae ie cyanobacteria have also been increasing reported at Canadian public beaches in recent years These algal blooms can cause various acute illnesses among recreational water users through ingestion inhalation of aerosols or skin contact with contaminated water In addition blue-green algae blooms and their toxins can cause illnesses in pets and wildlife Currently baseline data are lacking on the risk of recreational water illness from exposure to blue-green algae blooms in Canada This study will identify the burden of recreational water illness among recreational water users at four targeted beach sites in Ontario Manitoba and Nova Scotia over a two-year period A prospective cohort study design will be used We will determine the risk of acquiring acute illness outcomes in recreational water users as well as their pet dogs that engage in different levels of water contact at beaches at risk of blue-green algae blooms We will examine differences in illness risks by gender age and location We will examine relationships between cyanobacterial cell counts toxin levels and environmental conditions with the risk of acute illness among participants Overall results will provide important data on the risk of recreational water illness from exposure to blue-green algae and their toxins in Canadian beach settings
Detailed Description:
This study will investigate the incidence of recreational water illness due to exposure to cyanobacterial blooms and their toxins in four targeted and popular freshwater beaches in Ontario Manitoba and Nova Scotia Canada A prospective cohort design and One Health approach will be used On-site recruitment of recreational water users will be conducted at two beaches per year during the summers of 2024 and 2025 The population of interest includes recreational water users of any age and their pet dogs After enrollment an in-person survey will determine beach exposures and confounding factors and a three-day follow-up survey will ascertain any acute illness outcomes experienced by participants or their dogs The target sample size is 2500 recreational water users Water samples will be taken each recruitment day and analyzed for cyanobacterial indicators pigments cell counts and toxin levels Regression analysis will be conducted to estimate the association with water contact cyanobacterial levels and risks of different acute illness outcomes
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None