Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06582992
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-08-31
Brief Title:
DNA Methylation Trajectories in Aging
Sponsor:
None
Organization:
None
Study Overview
Official Title:
EPIGENETIC-SENSITIVE BIOMARKERS OF INFLAMMAGING FROM HEALTHY TO HEART FAILURE DISEASE
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
EPI-GERAS
Brief Summary:
The goal of this observational study is to profile changes in DNA methylation of circulating CD4 T and CD8 T cells from healthy young to aged with diagnosis of HFpEF a particular phenotype of HF which is highly prevalent in aging
The main question it aims to answer is
-Do DNA methylation biomarkers help us to understand the role of inflammation in HFpEF during aging
Our goal is to provide a simple large-scale panel of epigenetic-sensitive biomarkers useful in aged patients with HF in the early natural history of the disease HFpEF
The main question it aims to answer is
-Do DNA methylation biomarkers help us to understand the role of inflammation in HFpEF during aging
Our goal is to provide a simple large-scale panel of epigenetic-sensitive biomarkers useful in aged patients with HF in the early natural history of the disease HFpEF
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None