Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06583200
Status:
ENROLLING_BY_INVITATION
Last Update Posted:
None
First Post:
2024-08-03
Brief Title:
Fluid Responsiveness in Post Cardiac Surgery Patients
Sponsor:
None
Organization:
None
Study Overview
Official Title:
End Expiratory Occlusion Test for Evaluation of Fluid Responsiveness in Comparison to Passive Leg Raising Test in Mechanically Ventilated Post Cardiac Surgery Patients
Status:
ENROLLING_BY_INVITATION
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
Cardiac
Brief Summary:
The aim of the study is to compare end expiratory occlusion test to passive leg raising test for prediction of fluid responsiveness in post cardiac surgery mechanically ventilated patients
Detailed Description:
Circulatory hypervolemia and hypovolemia are both associated with worse outcomesIntravenous fluids are similar to drugs with serious adverse effects and changeful efficacy Fluids should be administered only if indicated Passive leg raising test transiently increase venous return which can be used to evaluate fluid responsivenessThere is growing evidence that the End expiratory occlusion EEO test reliably detects fluid responsiveness In patients under mechanical ventilation the inspiration increases intra-thoracic pressure and decreases venous return The expiratory hold augments the cardiac preload which in case of preload responsiveness leads to a significant increase of cardiac output COEEO prevents any variation in intra-thoracic pressure leading to an increase in venous return cardiac preload and stroke volume in preload-responsive patients Therere no studies comparing EEO with passive leg raising test in cardiac surgery patients So this is the target of the study
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None