Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06586736
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-08-30
Brief Title:
Physiological Studies in the Prone Position in Patients With ARDS
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The Respiratory Physiologic Efficacy of Prone Position and Its Association With Outcomes in ARDS A Prospective Observational Cohort Study
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to observe the changes of physiological indicators such as ventilation and oxygenation in the prone position of ARDS patients to observe the change trend of each patients indicators and to observe whether different trends of indicators predict different prognosis of patients
Detailed Description:
PP has been shown to effectively improve the prognosis of patients with severe ARDS but not all patients with ARDS can benefit from PP and the implementation of the PP has a certain clinical risks and side effects we lack a convenient predictors to guide doctors to determine whether patients should implement the PP Clinical usually observe the PF improved as whether PP treatment effective reference but there are literature points out that the rising PF after PP can not predict the better prognosis one of the mechanisms for ARDS patients benefit from PP is proved to be improve VQ the change of the VQ may determine whether the PP treatment effectively is an important indicator PaO2FiO2 ratio was usually used to evaluate the effect of PP but some studies did not support this conclusion PP has been shown to change ventilation-perfusion ratio dead space may be better physiological indicators simplify dead space ratio and Ventilatory ratio can be easily accessed at bedside and is associated with mortality of patients with ARDS The purpose of this study is to observe the predictive value of PF VD-etCO2VT and VR on the treatment effect of ARDS undergoing PP
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None