Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06588816
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-09-06
Brief Title:
The Correlation Between Pupil Size and Retinal Nerve Fibers Changes in Pseudoexfoliation Syndrome
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The Correlation Between Pupil Size and Retinal Nerve Fibers Changes in Pseudoexfoliation Syndrome
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To study the possible correlation between pupillary diameter before and after dilation with intraocular pressure lens stability and glaucomatous damage represented by optic disc changes using cup to disc ratio and OCT changes in retinal nerve fiber layer and ganglion cell complex in each eye of the same patient with PEX
Detailed Description:
Pseudoexfoliation PEX is a widespread condition that is often considered as a generalized disorder involving ocular manifestations as well as other body systems It is characterized by the deposition of a distinctive fibrillar material in the anterior segment of the eye The effect of pseudoexfoliation on various ocular tissues has been well studied in the past decades especially both lens and optic disc damage Key signs in pseudoexfoliative eyes are attributed to the effect of pseudoexfoliation material on pupillary muscles lens and optic disc Pseudoexfoliation appears to be a common disorder in older individuals in Upper Egypt with a prevalence of 414 PXF was bilateral in 822 of cases It was significantly associated with cataract glaucoma and hearing loss Of the PXF patients 65 had cataract 303 had glaucoma and 81 had hearing loss Cardiovascular and cerebrovascular diseases such as angina aortic aneurysm and dementia have been linked to PXS Subjects with PXF had a two- to three-fold increased risk for glaucoma according to the Blue Mountains Eye Study The classic sign of PXF is the visualization of white pseudoexfoliative material on the pupil margin and on the anterior lens surface It is believed that pupil size is another indicator for the severity of the disease In this study we correlate the pupil size with other common ocular signs in PEX such as lens subluxation and glaucomatous damage
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None