Ignite Creation Date:
2024-10-26 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 3:39 PM
Study NCT ID:
NCT06589193
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-08-29
Brief Title:
Comparison of the Clinical and Microbiological Effects of CHX and HOCl Containing Mouthwashes
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Comparison of the Clinical and Microbiological Effects of CHX and HOCl Containing Mouthwashes
Status:
COMPLETED
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The primary objective of the study is to compare the antiplaque and anti-inflammatory effects of HOCl mouth rinse with those of CHX mouth rinse The secondary objective is to evaluate and compare the antimicrobial activities of HOCl mouth rinse and CHX mouth rinse on dental biofilm
Detailed Description:
The primary objective of the current clinical study is to compare the antiplaque and anti-inflammatory efficacy of HOCl mouth rinse with that of CHX mouth rinse The secondary objective is to compare the antimicrobial activities of these two mouth rinses on dental biofilm This single-center triple-blind randomized controlled crossover study was completed with 26 participants In the study the same participants used both HOCl 002 and CHX 02 mouth rinses over a 4-day re-plaque formation model Following each mouth rinse usage supragingival dental plaque biofilm samples were collected and clinical parameters including the Modified Plaque Index Bleeding on Probing Index and Modified Stain Index were recorded Additionally participants were asked to evaluate the mouth rinses they used via a questionnaire In conclusion HOCl mouth rinse has demonstrated antiplaque efficacy comparable to that of CHX mouth rinse When evaluating total bacterial counts both mouth rinses exhibited similar antimicrobial effectiveness Within the limitations of this study HOCl may be considered a promising antimicrobial agent for dental plaque control
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None