Ignite Creation Date:
2024-10-26 @ 3:40 PM
Last Modification Date:
2024-10-26 @ 3:40 PM
Study NCT ID:
NCT06592092
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-03-17
Brief Title:
Clinical Study of QH104 Cell Injection for the Treatment of Meningeal Metastases of B7H3 Solid Tumors
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Clinical Study of QH104 Cell Injection for the Treatment of Meningeal Metastases of B7H3 Solid Tumors
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This is an open single-arm single-center interventional clinical study It is planned to enroll 3-6 patients with meningeal metastases from B7H3 solid tumors and to explore on a small scale the efficacy of local injection of allogeneic B7H3 CAR-γδ T cells 3107dose for the treatment of patients with meningeal metastases from B7H3 solid tumors
Detailed Description:
This study is an open single-arm single-center interventional clinical study It is planned to enroll 3-6 patients with meningeal metastases from B7H3 solid tumors and to explore on a small scale the clinical response to local injection of allogeneic B7H3 CAR-γδ T cells 3107dose for the treatment of patients with meningeal metastases from B7H3 solid tumors During the period of cell therapy the enrolled subjects may be given additional multiple infusions of cells after imaging neurological function cerebrospinal fluid cytology or the investigators assessment of the potential benefit of continuing cell therapy It is recommended that the frequency of multiple infusions be 2 weeks each and the interval between infusions can be adjusted at a later stage based on the PK and clinical symptoms of the subject after infusion
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None