Official Title: Short-term Astaxanthin Supplementation Enhances Cycling Performance and Attenuates Exhaustive Exercise-induced Muscle Damage and Oxidative Stress in Young Healthy Adults A Randomized Controlled Trial
Status: COMPLETED
Status Verified Date: 2024-09
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: No
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Ten young healthy physically active male college students were crossed over for AST or placebo supplements randomized into placebo or AST trials and orally consumed placebo or AST 28 mgd supplements for four days Short-term AST supplementation enhanced endurance performance and effectively reversed cycling challenge-induced muscle damage and lipid peroxidation
Detailed Description: AST is composed of two β-ionone ring systems that are linked by a polyene chain and contain oxygenated keto and hydroxyl moieties which are responsible for its powerful antioxidant activity AST has been shown to have numerous health benefits in humans including improved antioxidant and inflammatory status under different stress conditions Therefore this study will explore AST supplement to improve exercise-induced muscle damage andor physiological anomalies in adults Ten physically active male adults were randomized into placebo or AST trials and consumed placebo or AST 28 mgd supplements orally for 4 days On day-4 participants performed an exhaustive cycling challenge at 75 VO2max and the time to exhaustion TTE was recorded Blood and gaseous samples were collected before during and immediately after cycling to determine changes in muscle damage inflammation oxidative stress and substrate utilization