Ignite Creation Date:
2024-10-26 @ 3:40 PM
Last Modification Date:
2024-10-26 @ 3:40 PM
Study NCT ID:
NCT06593600
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-09-09
Brief Title:
Study of Natriuretic Peptide Receptor 1 NPR1 Antagonist in Adult Patients With Postural Orthostatic Tachycardia Syndrome POTS
Sponsor:
None
Organization:
None
Study Overview
Official Title:
A Phase 2 Double-Blind Placebo-Controlled Single-Dose Study of Pharmacodynamics Pharmacokinetics Safety and Tolerability of REGN7544 an NPR1 Antagonist Monoclonal Antibody in Patients With Postural Orthostatic Tachycardia Syndrome
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study is researching an experimental drug called REGN7544 called study drug The study is focused on participants with POTS
The aim of the study is to see how safe tolerable and effective the study drug is
The study is looking at several other research questions including
How the study drug changes heart rate and blood pressure in participants with POTS
What side effects may happen from taking the study drug
How much study drug is in the blood at different times
Whether the body makes antibodies against the study drug which could make the study drug less effective or could lead to side effects
The aim of the study is to see how safe tolerable and effective the study drug is
The study is looking at several other research questions including
How the study drug changes heart rate and blood pressure in participants with POTS
What side effects may happen from taking the study drug
How much study drug is in the blood at different times
Whether the body makes antibodies against the study drug which could make the study drug less effective or could lead to side effects
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None