Ignite Creation Date:
2024-10-26 @ 3:40 PM
Last Modification Date:
2024-10-26 @ 3:40 PM
Study NCT ID:
NCT06595979
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-09-04
Brief Title:
Intraventricular Administration of Intracranial Infections Caused by Carbapenem-resistant Gram-negative BacilliCRGNB
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Comparison of Intracranial Versus Intracranial Plus Intravenous Administration of Polymyxin B for the Treatment of Intracranial Infections Due to CRGNB
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This clinical trial aims to compare two methods of administering polymyxin B for treating severe brain infections caused by carbapenem-resistant Gram-negative bacteria CRGNB The two methods are 1 delivering polymyxin B directly into the brain intracranial administration and 2 combining this with an intravenous IV infusion The goal is to determine which approach is more effective in clearing the infection improving patient outcomes and influencing the concentration of polymyxin B in the cerebrospinal fluid CSF Participants in this study will be monitored for both effectiveness and safety with a focus on CSF polymyxin B levels to find the best treatment strategy for these challenging infections
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None