Ignite Creation Date:
2024-10-26 @ 3:40 PM
Last Modification Date:
2024-10-26 @ 3:40 PM
Study NCT ID:
NCT06603129
Status:
COMPLETED
Last Update Posted:
None
First Post:
2022-09-28
Brief Title:
Preoperative Prognostic Nutritional Index and Postoperative Delirium in Gastrointestinal Cancer Surgery
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Evaluation of the Relationship Between Preoperative Prognostic Nutritional Index and Postoperative Delirium in Gastrointestinal Cancer Surgery
Status:
COMPLETED
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Aim
We aimed to show the relationship between preoperative prognostic nutritional index and postoperative delirium in patients who had undergone gastrointestinal cancer surgery
Materials and Methods
Our study is a single-center prospective observational study Routine preoperative anesthesia evaluation of all patients was performed and patients age sex ASA physical score body mass index BMI existing comorbid diseases level of education smoking status cancer diagnosis chemotherapy and radiotherapy history type of surgery past invasive interventions concentration of hemoglobin and albumin lymphocyte count liver and kidney function tests were recorded PNI score was calculated with the preoperative measurements With the calculated PNI score nutritional status was defined as normal PNI 50 mild malnutrition PNI 45-50 moderate-severe malnutrition PNI 40-45 and severe PNI 40 accordingly The patients were then evaluated for the presence of delirium using the Confusion Assessment Method CAM for 3 days postoperatively
We aimed to show the relationship between preoperative prognostic nutritional index and postoperative delirium in patients who had undergone gastrointestinal cancer surgery
Materials and Methods
Our study is a single-center prospective observational study Routine preoperative anesthesia evaluation of all patients was performed and patients age sex ASA physical score body mass index BMI existing comorbid diseases level of education smoking status cancer diagnosis chemotherapy and radiotherapy history type of surgery past invasive interventions concentration of hemoglobin and albumin lymphocyte count liver and kidney function tests were recorded PNI score was calculated with the preoperative measurements With the calculated PNI score nutritional status was defined as normal PNI 50 mild malnutrition PNI 45-50 moderate-severe malnutrition PNI 40-45 and severe PNI 40 accordingly The patients were then evaluated for the presence of delirium using the Confusion Assessment Method CAM for 3 days postoperatively
Detailed Description:
Aim
Malnutrition common among gastrointestinal cancer patients affects morbidity and mortality Prognostic nutritional index PNI is an inflammation-based scoring that measures the nutritional and immunological status of patients and has been used to determine prognosis and predict postoperative complications Postoperative delirium POD describes a neurocognitive complication that may occur after surgery and anesthesia Most of the studies examining the relationship between PNI and POD are retrospective and the number of prospective large case series are insufficient
In this study we aimed to show the relationship between preoperative prognostic nutritional index and postoperative delirium in patients who had undergone gastrointestinal cancer surgery
Materials and Methods
Our study is a single-center prospective observational study Routine preoperative anesthesia evaluation of all patients was performed and patients age sex ASA physical score body mass index BMI existing comorbid diseases level of education smoking status cancer diagnosis chemotherapy and radiotherapy history type of surgery past invasive interventions concentration of hemoglobin and albumin lymphocyte count liver and kidney function tests were recorded PNI score was calculated with the preoperative measurements With the calculated PNI score nutritional status was defined as normal PNI 50 mild malnutrition PNI 45-50 moderate-severe malnutrition PNI 40-45 and severe PNI 40 accordingly The patients were then evaluated for the presence of delirium using the Confusion Assessment Method CAM for 3 days postoperatively
Malnutrition common among gastrointestinal cancer patients affects morbidity and mortality Prognostic nutritional index PNI is an inflammation-based scoring that measures the nutritional and immunological status of patients and has been used to determine prognosis and predict postoperative complications Postoperative delirium POD describes a neurocognitive complication that may occur after surgery and anesthesia Most of the studies examining the relationship between PNI and POD are retrospective and the number of prospective large case series are insufficient
In this study we aimed to show the relationship between preoperative prognostic nutritional index and postoperative delirium in patients who had undergone gastrointestinal cancer surgery
Materials and Methods
Our study is a single-center prospective observational study Routine preoperative anesthesia evaluation of all patients was performed and patients age sex ASA physical score body mass index BMI existing comorbid diseases level of education smoking status cancer diagnosis chemotherapy and radiotherapy history type of surgery past invasive interventions concentration of hemoglobin and albumin lymphocyte count liver and kidney function tests were recorded PNI score was calculated with the preoperative measurements With the calculated PNI score nutritional status was defined as normal PNI 50 mild malnutrition PNI 45-50 moderate-severe malnutrition PNI 40-45 and severe PNI 40 accordingly The patients were then evaluated for the presence of delirium using the Confusion Assessment Method CAM for 3 days postoperatively
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None