Ignite Creation Date:
2024-10-26 @ 3:40 PM
Last Modification Date:
2024-10-26 @ 3:40 PM
Study NCT ID:
NCT06604806
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-09-17
Brief Title:
Comparison of Quadroiliac Plane Block and Pericapsular Nerve Group PENG Block in Femoral Fractures
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Comparison of Postoperative Analgesic Efficacy of Quadroiliac Plane Block and Pericapsular Nerve Group PENG Block in Femoral Fractures A Multicenter Randomized Controlled Prospective Study
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This prospective multicenter study will compare the postoperative analgesic efficacy of the Quadroiliac Plane Block QIPB and Pericapsular Nerve Group PENG block in patients undergoing femoral neck fracture surgery Eligible patients will be randomly assigned to receive one of the blocks postoperatively under spinal anesthesia The blocks will be administered by experienced anesthesiologists and informed consent will be obtained from all participants
Pain levels will be assessed using the visual analog scale VAS at rest and during movement at 0 6 12 and 24 hours post-surgery Opioid consumption will be recorded through patient-controlled analgesia PCA and any need for rescue analgesia will be evaluated Routine postoperative pain management will also include intravenous paracetamol
Pain levels will be assessed using the visual analog scale VAS at rest and during movement at 0 6 12 and 24 hours post-surgery Opioid consumption will be recorded through patient-controlled analgesia PCA and any need for rescue analgesia will be evaluated Routine postoperative pain management will also include intravenous paracetamol
Detailed Description:
This prospective multicenter observational study will be conducted at Başakşehir Çam and Sakura City Hospital and Kanuni Sultan Süleyman Training and Research Hospital The study will include patients aged 18 and older with an ASA score of I-II-III undergoing femoral neck fracture surgery under spinal anesthesia Patients with no history of bleeding diathesis anticoagulant use or allergies to the drugs used in the study and without neuropathic diseases such as diabetes mellitus will be randomly assigned to receive either the Pericapsular Nerve Group PENG block or the Quadroiliac Plane Block QIPB postoperatively
Informed consent will be obtained from all patients and detailed explanations of both blocks will be provided Randomization will be performed using a computer program assigning patients to either block method Sealed envelopes will be provided to the anesthesiologists who will apply the block indicated in the envelope at the end of surgery Both blocks will be performed by experienced anesthesiologists and only patients operated on under spinal anesthesia will be included in the study
PENG Block Procedure
With the patient in the supine position the ultrasound probe is placed transversely over the anterior superior iliac spine ASIS After identifying the ASIS the transducer is aligned with the pubic ramus and rotated approximately 45 degrees to become parallel to the inguinal crease The transducer is moved medially until the anterior inferior iliac spine AIIS iliopubic eminence IPE and psoas tendon are clearly visualized as anatomical landmarks After confirming the correct location with saline injection 50 mg of 025 bupivacaine will be administered
QIP Block Procedure
With the patient in the prone position a low-frequency convex transducer 2-6 MHz and a 22G x 100 mm peripheral nerve block needle Stimuplex Ultra 360 B-Braun will be used The transducer will be placed transversely at the L3 level to identify the spinal processes followed by lateral movement to visualize the transverse process within the erector spinae muscle The transducer will then be rotated parasagittally and moved caudally to locate where the Quadratus Lumborum muscle QLM attaches to the iliac crest After confirming the location with saline 50 mg of 025 bupivacaine will be administered under the fascia of the QLM
Postoperative Analgesia
Patients will receive intravenous patient-controlled analgesia PCA with 2 mgmL Tramadol HCl in 100 mL NaCl solution delivered via bolus doses of 20 mg with a 20-minute lockout period and a total dose limit of 200 mg over 4 hours Pain scores using the visual analog scale VAS will be recorded at rest and with movement at 0 6 12 and 24 hours The total opioid consumption and the need for rescue analgesia 50 mg deksketoprofen in 100 mL mediflex over 20 minutes will also be assessed Routine administration of 1 g of intravenous paracetamol will be given at 6 hours postoperatively
Informed consent will be obtained from all patients and detailed explanations of both blocks will be provided Randomization will be performed using a computer program assigning patients to either block method Sealed envelopes will be provided to the anesthesiologists who will apply the block indicated in the envelope at the end of surgery Both blocks will be performed by experienced anesthesiologists and only patients operated on under spinal anesthesia will be included in the study
PENG Block Procedure
With the patient in the supine position the ultrasound probe is placed transversely over the anterior superior iliac spine ASIS After identifying the ASIS the transducer is aligned with the pubic ramus and rotated approximately 45 degrees to become parallel to the inguinal crease The transducer is moved medially until the anterior inferior iliac spine AIIS iliopubic eminence IPE and psoas tendon are clearly visualized as anatomical landmarks After confirming the correct location with saline injection 50 mg of 025 bupivacaine will be administered
QIP Block Procedure
With the patient in the prone position a low-frequency convex transducer 2-6 MHz and a 22G x 100 mm peripheral nerve block needle Stimuplex Ultra 360 B-Braun will be used The transducer will be placed transversely at the L3 level to identify the spinal processes followed by lateral movement to visualize the transverse process within the erector spinae muscle The transducer will then be rotated parasagittally and moved caudally to locate where the Quadratus Lumborum muscle QLM attaches to the iliac crest After confirming the location with saline 50 mg of 025 bupivacaine will be administered under the fascia of the QLM
Postoperative Analgesia
Patients will receive intravenous patient-controlled analgesia PCA with 2 mgmL Tramadol HCl in 100 mL NaCl solution delivered via bolus doses of 20 mg with a 20-minute lockout period and a total dose limit of 200 mg over 4 hours Pain scores using the visual analog scale VAS will be recorded at rest and with movement at 0 6 12 and 24 hours The total opioid consumption and the need for rescue analgesia 50 mg deksketoprofen in 100 mL mediflex over 20 minutes will also be assessed Routine administration of 1 g of intravenous paracetamol will be given at 6 hours postoperatively
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None