Official Title: Exercise in Patients With Atrial Fibrillation Effect of Different Types of Exercise on the Burden of the Pathology on the Biochemical Profile and on the Functional Capacity of the Patients
Status: NOT_YET_RECRUITING
Status Verified Date: 2024-09
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: No
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Atrial fibrillation AF significantly affects quality of life and increases the demand for medical care of those affected It is very important to identify triggering factors such as oxidative stress or N-terminal pro-B-type natriuretic peptide NT-proBNP as well as to identify potential biomarkers through plasma analysis At the same time it is essential to establish adequate training and rehabilitation programs which would result in a decrease in hospitalizations and the health care costs associated with the pathology Current cardiac rehabilitation programs based on physical exercise especially moderate intensity continuous training MICT have demonstrated effectiveness MICT improves cardiorespiratory fitness and quality of life in patients with AF However high-intensity intervallic training HIIT has shown superior benefits in these variables
Although HIIT traditionally has an aerobic focus a variant called high-intensity functional training HIFT is suggested that incorporates muscle strengthening exercises recommended in the guidelines for AF management This innovative modality seeks to achieve cardiovascular and neuromuscular adaptations simultaneously with a high transfer to daily activities Despite its potential the effects at the functional molecular and clinical levels in patients with AF are unknown The purpose of the study is to determine the benefits of HIFT on molecular functional and clinical variables in patients with AF and to compare these benefits with those achieved with HIIT and the usual care and recommendations in current clinical practice