Ignite Creation Date:
2024-10-26 @ 3:41 PM
Last Modification Date:
2024-10-26 @ 3:41 PM
Study NCT ID:
NCT06617494
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-09-24
Brief Title:
Endogenous Pain Inhibition Deficiency in Chronic TMD Pain
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The Role of Endogenous Pain Inhibition Deficiency in Chronic TMD Pain Pathophysiology
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
TMD-CPM
Brief Summary:
Temporomandibular disorders TMDs involve a range of conditions with varied causes affecting a large portion of the US population and posing challenges for diagnosis and management especially in chronic cases Despite advances in understanding TMD pathophysiology the role of central sensitization particularly deficient endogenous pain inhibition remains unclear The conditioned pain modulation CPM test used to assess pain inhibition in chronic TMD pain has produced inconsistent results due to varying testing parameters The proposed cross-sectional study will investigate the efficiency of endogenous pain inhibition in individuals with chronic TMD pain compared to controls by applying noxious and non-noxious stimuli to facial and non-facial sites The findings aim to clarify the impact of weaker pain inhibition over the face how the conditioning stimulus painfulness affects inhibition and the relationship between pain inhibition and fluctuations in TMD pain intensity
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None