Ignite Creation Date:
2024-10-26 @ 3:41 PM
Last Modification Date:
2024-10-26 @ 3:41 PM
Study NCT ID:
NCT06617988
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-09-23
Brief Title:
SIRT3 Expression in Granulosa Cells and the Levels of Follicular Fluid Metabolites Among POR Subgroups
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Investigate Differences in SIRT3 Expression in Granulosa Cells and the Levels of Follicular Fluid Metabolites Among Poor Ovarian Responders Subgroups and Their Association with IVF Outcomes
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
POR SIRT3
Brief Summary:
The goal of this prospective observational study is to learn about the pathogenesis and biological target of the subtypes of poor ovarian response POR during In vitro fertilization and embryo transfer IVF-ET The main question it aims to answer is
1 Can the relative expression level of SIRT3 differentiate between POR subtypes and do these differences reflect distinct metabolic characteristics among the subtypes
2 Investigate whether SIRT3 expression levels correlate with clinical outcomes This study will enroll patients with various POR subtypes and collect discarded follicular fluid and granulosa cells on the day of egg retrieval IVF outcome information routinely collected in electronic databases will also be recorded Notably this is a purely observational study with no additional interventions Your participation will not alter your clinical treatment compared to other patients
1 Can the relative expression level of SIRT3 differentiate between POR subtypes and do these differences reflect distinct metabolic characteristics among the subtypes
2 Investigate whether SIRT3 expression levels correlate with clinical outcomes This study will enroll patients with various POR subtypes and collect discarded follicular fluid and granulosa cells on the day of egg retrieval IVF outcome information routinely collected in electronic databases will also be recorded Notably this is a purely observational study with no additional interventions Your participation will not alter your clinical treatment compared to other patients
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None