Ignite Creation Date:
2024-10-26 @ 3:42 PM
Last Modification Date:
2024-10-26 @ 3:42 PM
Study NCT ID:
NCT06627868
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-10-02
Brief Title:
Nicotinamide Adenine Dinucleotide NAD Metabolism in Human Brown Adipose Tissue
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Nicotinamide Adenine Dinucleotide NAD Metabolism in Human Brown Adipose Tissue
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
BATNAD
Brief Summary:
A fully functional brown fat helps maintain a healthy weight and decreases the risk of metabolic diseases such as type II diabetes T2DM Unfortunately in human adults the functionality of brown fat declines with age and it is one of the reasons for gaining unhealthy weight particularly around the waistline central obesity Currently we do not clearly understand the reasons for the decline in brown fat functionality It is possible that the decline in the availability of the molecule Nicotinamide Adenine Dinucleotide NAD which is central to several metabolic processes plays a role in the decline in brown fat metabolism This project will clarify whether NAD-based molecular-targeted therapies for the enhancement of whole-body insulin sensitivity and brown fat metabolism will be successful in adult humans which will eventually be an important target for reducing the development of obesity and its comorbidities such as T2DM
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None