Ignite Creation Date:
2024-10-26 @ 3:42 PM
Last Modification Date:
2024-10-26 @ 3:42 PM
Study NCT ID:
NCT06628479
Status:
COMPLETED
Last Update Posted:
None
First Post:
2024-06-09
Brief Title:
Relaxin Matrix Metalloproteinase-2 and Interleukin-6 in Women With Chronic Pelvic Pain
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Relaxin Matrix Metalloproteinase-2 and Interleukin-6 in Women With Chronic Pelvic Pain Diagnosis of Deep Infiltrative Endometriosis and Investigation of it is Place in Follow-up
Status:
COMPLETED
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In our study by evaluating the serum and vaginal-peritoneal fluid levels of Relaxin Matrix Metalloproteinase-2 and Interleukin-6 in women over 35 years of age with chronic pelvic pain the investigators aimed to reveal their potential to be an important marker in the diagnosis of Deep Infiltrative Endometriosis thus enabling early diagnosis with lower cost and results that can be obtained in a short timeThe investigators aim to reveal its relationship with follow-up
In our study the values of Relaxin MMP-2 or IL-6 from vaginal fluids were found to be significantly higher than the control group in the prediction and follow-up of deep infiltrative endometriosis This supports the role of Relaxin and MMP-2 as well as IL-6 in the pathophysiology of deep infiltrative endometriosis
Histologically based and multicenter randomized controlled studies with more patients are needed to elucidate the etiology and pathophysiology of endometriosis
In our study the values of Relaxin MMP-2 or IL-6 from vaginal fluids were found to be significantly higher than the control group in the prediction and follow-up of deep infiltrative endometriosis This supports the role of Relaxin and MMP-2 as well as IL-6 in the pathophysiology of deep infiltrative endometriosis
Histologically based and multicenter randomized controlled studies with more patients are needed to elucidate the etiology and pathophysiology of endometriosis
Detailed Description:
10 cc of vaginal washing fluid serum samples on the day of operation and 20 cc of pelvic washing fluid during laparoscopy were taken from all patients before the operation Patients were included in the FA group according to the ENZIAN Classification Patients age BMI gravida parity obstetric history such as pregnancy ethnic origin educational status preoperative and postoperative evaluation for chronic pelvic pain laboratory tests routine tests such as Ca125 CRP FSH LH E2 P Preoperative and postoperative hormonal values were recorded Relaxin MMP-2 and IL-6 values from vaginal washing fluid peritoneal washing fluid and serum samples of the patients in the control and study groups were compared
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None