Ignite Creation Date:
2024-10-26 @ 3:42 PM
Last Modification Date:
2024-10-26 @ 3:42 PM
Study NCT ID:
NCT06630377
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-07-03
Brief Title:
GOS and the Management of Hyperuricemia
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The Effectiveness of Galactooligosaccharide on the Treatment of Hyperuricemia
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Hyperuricemia is a major risk factor for many chronic diesease Recently gut mcirobiota has been identified as a novel therapeutic target for hyperuricemia Both annimal studies and pilot human trials have demonstrated that administration of prebiotics help delay the progression of hyperuricemia throuh several mechanisms This trial aims to examine the protective effects and potential mechanisms of galactooligosaccharide on hyperuricemia in clinical trials
Detailed Description:
Hyperuricemia is a major risk factor for many chronic diseases Recently dysbiosis of gut microbiota has been reported to play an important role in the pathogenesis of hyperuricemia Animal studies have demonstrated that administration of prebiotics help delay the progression of hyperuricemia through several mechanisms such as reduction in endotoxemia and enhanced production of short-chain fatty acids and hippuric acid
However whether administration of galactooligosaccharide also has a protective effect in subjects with hyperuricemia remain under-explored Moreover the molecular mechanisms underlying the protective effect of galactooligosaccharide remains largely unknown
However whether administration of galactooligosaccharide also has a protective effect in subjects with hyperuricemia remain under-explored Moreover the molecular mechanisms underlying the protective effect of galactooligosaccharide remains largely unknown
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None