Ignite Creation Date:
2024-10-26 @ 3:42 PM
Last Modification Date:
2024-10-26 @ 3:42 PM
Study NCT ID:
NCT06634524
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-10-08
Brief Title:
Effect of Dexmedetomidine on Gastric Emptying Assessed by Ultrasound in Laparoscopic Cholecystectomy
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The Effect of Dexmedetomidine on Gastric Emptying Assessed by Ultrasound in Patients Undergoing Laparoscopic Cholecystectomy A Prospective Randomized Trial
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study is to evaluate the effect of dexmedetomidine on gastric emptying assessed by gastric ultrasound in patients undergoing laparoscopic cholecystectomy
Detailed Description:
Delayed return of normal gastrointestinal function and postoperative nausea and vomiting PONV are common adverse events of laparoscopic cholecystectomy under general anesthesia Sympathetic stimulation intra-abdominal carbon dioxide insufflation and the consequent visceral peritoneal irritation are all contributing factors In addition anesthetic agents and opioids can also have a harmful impact on gastric emptying
Dexmedetomidine a potent and highly selective alpha-2 adrenoreceptor agonist is frequently employed as an anesthetic adjunct in surgical procedures By reducing the surgical stress response through its central sympatholytic and anti-inflammatory effects dexmedetomidine offers distinct organ protection Furthermore its opioid-sparing effect reduces the need for perioperative analgesics
A recent meta-analysis reported a positive impact of perioperative dexmedetomidine use on postoperative gastrointestinal function by shortening the time to pass flatusThe use of gastric ultrasound to assess cross-sectional area of the stomach and its volume may provide better insight into the effect of dexmedetomidine on gastrointestinal function
Dexmedetomidine a potent and highly selective alpha-2 adrenoreceptor agonist is frequently employed as an anesthetic adjunct in surgical procedures By reducing the surgical stress response through its central sympatholytic and anti-inflammatory effects dexmedetomidine offers distinct organ protection Furthermore its opioid-sparing effect reduces the need for perioperative analgesics
A recent meta-analysis reported a positive impact of perioperative dexmedetomidine use on postoperative gastrointestinal function by shortening the time to pass flatusThe use of gastric ultrasound to assess cross-sectional area of the stomach and its volume may provide better insight into the effect of dexmedetomidine on gastrointestinal function
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None