Ignite Creation Date:
2024-10-26 @ 3:42 PM
Last Modification Date:
2024-10-26 @ 3:42 PM
Study NCT ID:
NCT06638424
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-10-09
Brief Title:
Study of the Impact of Cataract Surgery on the Corneal Epithelium and Ocular Surface of Diabetic Patients
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Study of the Impact of Cataract Surgery on the Corneal Epithelium and Ocular Surface of Diabetic Patients
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
CATARA
Brief Summary:
Diabetes is one of the most common fatal metabolic diseases in the world Diabetes-induced ocular surface alterations are poorly understood Indeed it was once thought that the cornea avascular was immune to the effects of diabetes A growing number of publications now demonstrate the opposite These alterations affect up to 70 of diabetic patients at some point in the progression of their diabetes
Another common complication of diabetes is the early development of a cataract requiring surgery Diabetic patients are therefore more likely to require surgery at an early age than the general population
Diabetes and cataract surgery both induce corneal changes Cataract surgery in diabetic patients is therefore at greater risk of corneal complications Diabetes induces dysfunction of the main lacrimal gland corneal neuropathy meibomian dysfunction and a decrease in conjunctival mucus cells Diabetic patients are therefore particularly at risk of exacerbation or appearance of alterations of the corneal epithelium and the ocular surface in postoperative cataract surgery
Therefore it seems necessary to evaluate the impact of cataract surgery on the ocular surface and corneal epithelium of diabetic patients in order to improve their management
Another common complication of diabetes is the early development of a cataract requiring surgery Diabetic patients are therefore more likely to require surgery at an early age than the general population
Diabetes and cataract surgery both induce corneal changes Cataract surgery in diabetic patients is therefore at greater risk of corneal complications Diabetes induces dysfunction of the main lacrimal gland corneal neuropathy meibomian dysfunction and a decrease in conjunctival mucus cells Diabetic patients are therefore particularly at risk of exacerbation or appearance of alterations of the corneal epithelium and the ocular surface in postoperative cataract surgery
Therefore it seems necessary to evaluate the impact of cataract surgery on the ocular surface and corneal epithelium of diabetic patients in order to improve their management
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None