Ignite Creation Date:
2024-10-26 @ 3:43 PM
Last Modification Date:
2024-10-26 @ 3:43 PM
Study NCT ID:
NCT06644911
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-10-15
Brief Title:
Obesity Doppler in Term Pregnancy
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The Effect of Maternal Obesity on Umbilical and Uterine Artery Doppler in Term Pregnancy a Cross-sectional Study
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Maternal obesity is an epidemic in the developed world like Egypt There are many pregnancy-associated complications including pre-eclampsia gestational diabetes and increased rates of septic wound after cesarean delivery As a potential explanation of the etiology of complications due to maternal obesity the role of endothelial dysfunction in the systemic and peripheral vasculatures has been hypothesized 3 It has been proposed that some adverse pregnancy outcomes in obese patients may be mediated by placental insufficiency 4 Utero-placental insufficiency is typically associated with fetal growth restriction and low birth weight
Umbilical and uterine artery Doppler is widely accepted as a useful tool for monitoring high-risk pregnancies
Normally uterine artery vascular impedance gradually decreases until the late mid-trimester owing to the establishment of a low-resistance placental circulation Obesity has little impact on uterine vascular changes reflected by the early uterine artery PI However in the second trimester extreme obesity appears to impair the normal continued drop in uterine vascular resistance 9 Many studies have examined the relationship between BMI and Doppler changes in high-risk pregnancies but few studies addressed theses changes in low-risk pregnancies 10
Umbilical and uterine artery Doppler is widely accepted as a useful tool for monitoring high-risk pregnancies
Normally uterine artery vascular impedance gradually decreases until the late mid-trimester owing to the establishment of a low-resistance placental circulation Obesity has little impact on uterine vascular changes reflected by the early uterine artery PI However in the second trimester extreme obesity appears to impair the normal continued drop in uterine vascular resistance 9 Many studies have examined the relationship between BMI and Doppler changes in high-risk pregnancies but few studies addressed theses changes in low-risk pregnancies 10
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None