Ignite Creation Date:
2024-10-26 @ 3:43 PM
Last Modification Date:
2024-10-26 @ 3:43 PM
Study NCT ID:
NCT06645041
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-10-13
Brief Title:
The Impact of Vitamin D Supplementation in Hypertensive Vitamin D Deficient Patients
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The Relationship of Vitamin D and Irisin With Blood Pressure and Heart Rate Variability in Normotensive and Hypertensive Individuals The Impact of Vitamin D Supplementation in Hypertensive Vitamin D Deficient Patients
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will assess the impact of Vitamin D supplementation on hypertensive patients with Vitamin D deficiency it will also investigate the relationship between serum Vitamin D irisin levels blood pressure and heart rate variability HRV in hypertensive and normotensive individuals
It is hypothesized that a decrease in blood pressure and an increase in HRV will be noted in the hypertensive treatment group subjects on supplemental vitamin D in comparison to the hypertensive control group placebo upon vitamin D supplementation
It is hypothesized that a decrease in blood pressure and an increase in HRV will be noted in the hypertensive treatment group subjects on supplemental vitamin D in comparison to the hypertensive control group placebo upon vitamin D supplementation
Detailed Description:
In a prospective study conducted on 160 participants 80 hypertensive and 80 normotensive individuals assessing correlations between Vitamin D irisin blood pressure and HRV hypertensive vitamin D deficient participants will be recruited in a randomized controlled trial In this clinical trial 60 hypertensive participants with Vitamin D deficiency will receive either Vitamin D supplementation 25000 IU weekly or a placebo for 8 weeks 30 participants in each group
Outcome measures include systolic and diastolic blood pressure HRV serum Vitamin D and serum irisin levels before and after supplementation
The aim is to explore the potential role of Vitamin D and irisin in regulating blood pressure and improving HRV potentially offering preventive measures for hypertension management
Outcome measures include systolic and diastolic blood pressure HRV serum Vitamin D and serum irisin levels before and after supplementation
The aim is to explore the potential role of Vitamin D and irisin in regulating blood pressure and improving HRV potentially offering preventive measures for hypertension management
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None