Ignite Creation Date:
2024-10-26 @ 3:43 PM
Last Modification Date:
2024-10-26 @ 3:43 PM
Study NCT ID:
NCT06645405
Status:
RECRUITING
Last Update Posted:
None
First Post:
2024-10-09
Brief Title:
AI-Driven CTA Reconstruction for Intracranial LVO
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Segmentation and Modeling for Accurate Reconstruction of CT Angiography of Intracranial Large Vessel Occlusion with Artificial Intelligence a Stepped-wedge Cluster-randomized Controlled Trial
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
SMART-AI
Brief Summary:
Acute ischemic stroke AIS caused by intracranial large vessel occlusion LVO in the anterior circulation significantly contributes to stroke-related disability and mortality Recent randomized controlled trials have demonstrated substantial benefits of endovascular thrombectomy EVT when patients are appropriately triaged beforehand However accurately orienting the missed segment during EVT remains challenging Guide-wires often fail to navigate through the occlusion or are mistakenly directed into the small tranches or even cause vessel rupture To address this clinical need the investigators developed an artificial intelligence AI algorithm to automate the reconstruction of CT angiography CTA focusing on the occluded LVO segment To evaluate the clinical utility of this AI algorithm the investigators propose a prospective stepped-wedge cluster-randomized study to determine whether integrating our AI algorithm into AIS care flow can reduce the time for first pass of the thrombus by improving the visualization of the occluded segment on CTA Physicians will assess patient eligibility for thrombectomy and all selected patients will receive standard care according to current guidelines This approach is expected to enhance patient treatment outcomes for endovascular thrombectomy by leveraging readily available data
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None