Ignite Creation Date:
2024-10-26 @ 3:43 PM
Last Modification Date:
2024-10-26 @ 3:43 PM
Study NCT ID:
NCT06647641
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-10-16
Brief Title:
The CurePSP Genetics Program
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The CurePSP Genetics Program
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study is an observational prospective genetic study It aims to obtain DNA for research and testing from patients with PSP CBS MSA and related neurological conditions and their families
Up to 1000 adults who have been clinically diagnosed with PSP CBS MSA or related neurological conditions will be enrolled The study intervention involves sequencing of participant blood samples using non-CLIA-approved whole genome sequencing at the National Institutes of Health Pathogenic variants that are deemed possibly related to these conditions will be confirmed using CLIA-approved testing The study involves minimal risk to participants
Up to 1000 adults who have been clinically diagnosed with PSP CBS MSA or related neurological conditions will be enrolled The study intervention involves sequencing of participant blood samples using non-CLIA-approved whole genome sequencing at the National Institutes of Health Pathogenic variants that are deemed possibly related to these conditions will be confirmed using CLIA-approved testing The study involves minimal risk to participants
Detailed Description:
Genetic research is important for basic translational and clinical researchers and are particularly important for rare disease investigations Understanding a patients genetic background may also facilitate participant recruitment for targeted genetic therapeutic trials and has the potential to empower participants with PSP CBS MSA or related neurological diseases and clinicians to make more informed decisions about their clinical care plan Furthermore genetic research augments the clinical counseling process by offering participants and their families a clearer understanding of disease risk in relatives Overall this study may help to refine current diagnostic criteria for PSP CBS MSA and related neurological conditions inform genetic counseling fuel future research studies and provide insights into potential therapeutic paradigms
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None