Ignite Creation Date:
2024-10-26 @ 3:43 PM
Last Modification Date:
2024-10-26 @ 3:43 PM
Study NCT ID:
NCT06649370
Status:
ENROLLING_BY_INVITATION
Last Update Posted:
None
First Post:
2024-10-17
Brief Title:
Effect of Systemic Inflammatory Index and Systemic Immune Inflammation Index on Ecchymosis Bleeding and Edema
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Effect of Systemic Inflammatory Index and Systemic Immune Inflammation Index on Ecchymosis Bleeding and Edema in Rhinoplasty
Status:
ENROLLING_BY_INVITATION
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Rhinoplasty is a cosmetic surgical procedure that is widely applied today and is characterized by edema in the postoperative period In particular edema can cause prolonged recovery and deterioration in the patients social life Various studies have been conducted using certain drugs or different surgical techniques to reduce edema and ecchymosis in rhinoplasty
In rhinoplasty edema occurs after the absorption of interstitial fluid in the nose is disrupted as a result of trauma to the bone and soft tissue Ecchymosis occurs when blood passes from damaged vessels due to surgery to the loose and thin soft tissue around the eye Ecchymosis is often seen on the eyelids after open rhinoplasty Ecchymosis usually moves in the direction of gravity and increases in the first two days after surgery
Systemic inflammatory response index and systemic immune inflammation index can be easily obtained with a simple hemogram test These indexes have been suggested to be a useful parameter in many diseases associated with inflammation but research is still ongoing Inflammation values and the resulting response have an important effect on wound formation and healing However increased inflammation can also increase edema and ecchymosis in the postoperative period In this study the researchers aimed to investigate the relationship between preoperative inflammation values and postoperative edema and ecchymosis in open rhinoplasties
In rhinoplasty edema occurs after the absorption of interstitial fluid in the nose is disrupted as a result of trauma to the bone and soft tissue Ecchymosis occurs when blood passes from damaged vessels due to surgery to the loose and thin soft tissue around the eye Ecchymosis is often seen on the eyelids after open rhinoplasty Ecchymosis usually moves in the direction of gravity and increases in the first two days after surgery
Systemic inflammatory response index and systemic immune inflammation index can be easily obtained with a simple hemogram test These indexes have been suggested to be a useful parameter in many diseases associated with inflammation but research is still ongoing Inflammation values and the resulting response have an important effect on wound formation and healing However increased inflammation can also increase edema and ecchymosis in the postoperative period In this study the researchers aimed to investigate the relationship between preoperative inflammation values and postoperative edema and ecchymosis in open rhinoplasties
Detailed Description:
Although rhinoplasty is one of the most commonly performed facial surgical procedures intraoperative bleeding postoperative ecchymosis and edema negatively affect patient satisfaction No matter how gently and carefully the surgeon performs the procedure in rhinoplasty trauma inflammation and as a result edema and ecchymosis develop in the tissues Edema and ecchymosis can cause temporary vision loss permanent pigmentation and scar tissue Studies have been conducted using different drugs such as steroids adrenaline and lidocaine to reduce edema and ecchymosis in rhinoplasty surgery and different osteotomy techniques in rhinoplasty In patients undergoing rhinoplasty inflammation of the nasal mucosa at the osteotomy site is an important cause of periorbital edema and ecchymosis The systemic inflammatory response index is an easily accessible and calculable biomarker that provides important information about inflammatory conditions and inflammatory diseases This simple index shows the balance between regulatory and protective lymphocytes neutrophils and active inflammatory components In addition to inflammation this index also provides information about vascular involvement and damage in some diseases Leukocytes further increase inflammation in damaged vessels increasing endothelial damage and the risk of thrombus Rhinoplasty is a commonly performed surgical procedure and postoperatively even during the surgical procedure ecchymosis and edema can be seen around the eyes and face This affects the patients recovery discharge and return to social life Many studies have been conducted to reduce postoperative edema and ecchymosis in rhinoplasty However it is very important to be able to predict the severity of edema and ecchymosis in advance There are not enough studies on this subject and the results are contradictory Therefore the aim of this study was to investigate whether there is a relationship between the systemic inflammatory response index and systemic immune inflammation index which are measured before surgery in rhinoplasty and postoperative ecchymosis and edema
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None