Ignite Creation Date:
2024-10-26 @ 3:43 PM
Last Modification Date:
2024-10-26 @ 3:43 PM
Study NCT ID:
NCT06649799
Status:
ENROLLING_BY_INVITATION
Last Update Posted:
None
First Post:
2024-10-18
Brief Title:
Comparative Study on Changes in Anterior Chamber Cytokines Oxidative Stress and Pupil Size After LenSx and Z8 Femtosecond Lasers
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Comparative Study on Changes in Anterior Chamber Cytokines Oxidative Stress and Pupil Size After LenSx and Z8 Femtosecond Lasers
Status:
ENROLLING_BY_INVITATION
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Femtosecond laser-assisted cataract surgery is rapidly gaining popularity Among the 5 femtosecond laser platforms available at present for cataract surgery the Femto LDV Z8 Ziemer Ophthalmic Systems AG is a high-frequency system and delivers energy pulses in nanojoule levels while Lensx platform Lensx Alcon Laboratories Inc used a high-energy laser system In femtosecond laser-assisted cataract surgery the laser pretreatment is associated with breakdown of blood-aqueous barrier BAB associated with increased aqueous total prostaglandin cytokines and Oxygen-free radicals concentration The prostaglandin rise immediately after laser pretreatment is further thought to be the causative factor for the intraoperative miosis in femtosecond laser-assisted cataract surgery However the analysis of anterior chamber inflammatory factors oxidative stress and pupil size after femtosecond laser-assisted cataract surgery between different laser platforms has not been investigated in clinical studies Understanding the cytokine and chemokine changes related to the laser pretreatment provides better insight into the inflammatory response in femtosecond laser-assisted cataract surgery
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None