Ignite Creation Date:
2024-10-26 @ 3:43 PM
Last Modification Date:
2024-10-26 @ 3:43 PM
Study NCT ID:
NCT06650891
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-10-18
Brief Title:
Quercetin Effect on Post-ceserean Pain
Sponsor:
None
Organization:
None
Study Overview
Official Title:
The Adjunctive Effect of Quercetin on Postoperative Pain Management Following Cesarean Section
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The cesarean section is a common gynecological surgery requiring effective pain management to prevent complications and immobility Inadequate pain control can lead to longer hospital stays higher readmission rates and dissatisfaction with healthcare Traditional analgesics such as opioids have proven effective in alleviating pain but they can cause side effects Therefore researchers are exploring compounds that can reduce opioid analgesic needs and improve pain control Quercetin has anti-nociceptive effects in rodent models of chronic pain including inflammatory neuropathic and cancer pain There are limited clinical studies on the effect of quercetin on acute or chronic pain The current study is designed to assess the efficacy of preoperative quercetin administration in acute post-operative pain following cesarean section
Detailed Description:
The cesarean section is a common gynecological surgery accounting for 40-50 of deliveries in public hospitals Effective pain management following a cesarean delivery is crucial as inadequate control can hinder a mothers capacity to care for her newborn Uncontrolled postoperative pain can lead to patient immobility increasing the risk of thromboembolic complications Failure to adequately manage pain can result in economic and medical issues including longer hospital stays higher readmission rates increased patient recovery costs and patient dissatisfaction with the quality of healthcare provided
Opioid medications particularly when administered via injection have proven effective in alleviating acute pain but they are associated with dose-related side effects Therefore it is prudent to investigate compounds that can potentiate the analgesic effects of opioids enabling improved pain control while minimizing opioid consumption Quercetin a flavonoid and polyphenol found in various plants and fruits has been studied for its anti-inflammatory free radical scavenging antidiabetic anticancer cardiovascular hepatoprotective neuroprotective antiplatelet antibacterial and anti-obesity effects Recent evidence indicates quercetin possesses anti-nociceptive effects in rodent models of chronic pain including inflammatory pain neuropathic pain and cancer pain
Quercetin has great potential for clinical use in pain treatment as its safety is well established However there are limited clinical studies on the effect of quercetin on acute or chronic pain The current study aims to assess the efficacy of preoperative quercetin administration in acute post-operative pain following cesarean section
Opioid medications particularly when administered via injection have proven effective in alleviating acute pain but they are associated with dose-related side effects Therefore it is prudent to investigate compounds that can potentiate the analgesic effects of opioids enabling improved pain control while minimizing opioid consumption Quercetin a flavonoid and polyphenol found in various plants and fruits has been studied for its anti-inflammatory free radical scavenging antidiabetic anticancer cardiovascular hepatoprotective neuroprotective antiplatelet antibacterial and anti-obesity effects Recent evidence indicates quercetin possesses anti-nociceptive effects in rodent models of chronic pain including inflammatory pain neuropathic pain and cancer pain
Quercetin has great potential for clinical use in pain treatment as its safety is well established However there are limited clinical studies on the effect of quercetin on acute or chronic pain The current study aims to assess the efficacy of preoperative quercetin administration in acute post-operative pain following cesarean section
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None